Epigenetics in Organ Specific Disorders. (2022)

• Record Type: Book
• Further Information: Note: Chandra S. Boosani, Ritobrata Goswami.
• Editors: Boosani, Chandra S; Goswami, Ritobrata
• Contents: 1. Introduction to epigenetic mechanisms; 2. Epigenetic signatures that maintain stemness in pluripotent and mesenchymal stem cells; 3. Cell-cell and Cell-matrix interactions mediated by histone deacetylases; 4. Enhanced cell proliferation and altered gene expression due to actions of DNA methyltransferases; 5. Histone deacetylases and regulation of gene expression during cell proliferation; 6. Epigenetic mediators that promote cytoskeletal reorganization and cell migration; 7. Inhibition of cellular apoptosis and senescence by unique epigenetic proteins; 8. Epigenetic mechanisms involved in the regulation of necrosis and pyknosis; 9. Epigenetic control over cell division in pathological conditions; 10. Regulated expression of tumor suppressor proteins by DNA methyltransferases during cell cycle progression; 11. Role of histone deacetylases in regulating cell cycle progression; 12. Phenotype switch and cell differentiation in immune and non-immune cells regulated by different epigenetic mediators; 13. Epigenetic pathways that promote cellular autophagy; 14. Epigenetic inducers of Cell growth and survival; 15. Microbial compounds as potential inducers of epigenetic mechanisms during infections; 16. Current epigenetic drugs and their target proteins with potential use in disease treatment; 17. Prospects of epigenetic drugs in combination therapy
• Publisher Details: Academic Press
• Publication Date: 2022
• Extent: 1 online resource (666 pages)
• Languages: English
• ISBNs: 9780128239322; 0128239328
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.