Human and animal filariases : landscape, challenges, and control /: landscape, challenges, and control. (2022)

• Record Type: Book
• Further Information: Note: Edited by Ronald Kaminsky, Timothy G. Geary.
• Editors: Kaminsky, Ronald; Geary, Timothy G, 1952-
• Contents: PART I: Background, Status and Gaps; Filariae as organisms (including life cycles); Human filariasis - disease and current problems; Canine filariasis (heartworm) - disease and current problems/gaps; diagnosis of human filarial infections; diagnosis of canine filarial infections; Antifilarial chemotherapy: current options (human section); Antifilarial chemotherapy: current options (veterinary section); Current products; Current antifilarial drug - mode of action; Drug resistance in canine filarial chemotherapy; Eradication/elimination of human filariae; The economic impact of human filariasis; The economic impact of canine filariasis; ; PART II: Antifilarial Drug Discovery and Development; Product profiles of new antifilarial drugs -; Discovery and development of new antifilarial drugs (in vitro assays); Rodent models for the discovery of new antifilarial drugs; Discovery and development of new canine antifilarial drugs (in vivo assays); Discovery and development of new human antifilarial drugs (in vivo assays); The drug pipeline, including triple combination therapy, moxidectin, emodepside, TylaMac, auranofin; ; PART III: Alternative Approaches; Functional genomics of filariae; Vector control approaches: humans; Vector control approaches: canine; Drug targets at the host-parasite interface; Endosymbionts as targets; Vaccines: progress and prospects
• Edition: 1st
• Publisher Details: Weinheim : Wiley-VCH
• Publication Date: 2022
• Extent: 1 online resource
• Subjects: 595.7857; Parasitology; Parasitic diseases -- Treatment; Filariasis; Filarial worms
• Languages: English
• ISBNs: 9783527823420
• Related ISBNs: 9783527346592
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.