Overcoming resistance to EGFR inhibitors in EGFR mutant NSCLC. (2022)

• Record Type: Book
• Further Information: Note: Edited by Anthony Faber.
• Editors: Faber, Anthony
• Contents: 1. The EGFR in NSCLC: Biology, activation and targeting; 2. Background of the EGFR receptor, biology of activation, regulation of EGFR in normal cells and cancer cells, mutations as oncogenic in NSCLC; 3. Background of EGFR inhibitor development and implementation, assessment of how EGFR inhibitors have been implemented and are currently implemented; 4. YAP signalling in EGFR inhibitor resistance; 5. Apoptosis resistance in EGFR inhibitor resistance; 6. EGFR mutations and resistance to EGFR inhibitors; 7. SCLC transformation and resistance to EGFR inhibitors; 8. EMT and resistance to EGFR inhibitors in EGFR mutant NSCLC; 9. Intratumoral heterogeneity and resistance; 10. Clinical trials of EGFR inhibitors in EGFR mutant lung cancer; 11. Methodology of the detection of resistant mechanisms in the lung cancer clinic
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2022
• Extent: 1 online resource
• Subjects: 616.99424061; Lungs -- Cancer -- Chemotherapy; Drug resistance
• Languages: English
• ISBNs: 9780128228340
• Related ISBNs: 9780128228333
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.