Drug transporters : molecular characterization and role in drug disposition /: molecular characterization and role in drug disposition. (2022)

• Record Type: Book
• Further Information: Note: Edited by Guofeng You, Marilyn E. Morris.
• Editors: You, Guofeng; Morris, Marilyn Emily
• Contents: List of Contributors Preface CHAPTER 1. Overview of Drug Transporter Families; Guofeng You and Marilyn E. Morris CHAPTER 2. Organic Cation and Zwitterion Transporters; Megan L. Koleske, Xiaomin Liang, Osatohanmwen Jessica Enogieru, Dina Buitrago, and KathleenM. Giacomini CHAPTER 3. Multidrug and Toxin Extrusion Proteins; Lauren M. Aleksunes, Victoria Woo, and Melanie S. Joy CHAPTER 4. Organic Anion Transporters (OATs); Jeffry C. Granados, Jingui Zhang, Guofeng You, Sanjay K. Nigam CHAPTER 5. Organic Anion Transporting Polypeptides OATP; Rommel G. Tirona and Richard B. Kim CHAPTER 6. Mammalian Oligopeptide Transporters; Stephen M. Carl, Dea Herrera-Ruiz, Rajinder K. Bhardwaj, Olafur Gudmundsson, Stephanie Mowery, and Gregory T. Knipp. CHAPTER 7. Monocarboxylic Acid Transporters; Marilyn E. Morris and Nisha V. Kwatra CHAPTER 8. The Nucleoside Transporters CNTs and ENTs; Raj Govindarajan, Antonio López Quiñones, and Joanne Wang CHAPTER 9. Bile Acid Transporters; Ebehiremen N. Ayewoh and Peter W. Swaan CHAPTER 10. The P-glycoprotein Multidrug Transporter; Andaleeb Sajid, Sabrina Lusvarghi and Suresh V. Ambudkar CHAPTER 11. Multidrug Resistance Proteins of the ABCC Subfamily; Anne T. Nies and Franziska Klein CHAPTER 12. ABCG2, the Breast Cancer Resistance Protein (BCRP); Robert W. Robey, Sabrina Lusvarghi, Cindy H. Chau, Agnes Basseville, William D. Figg, Suresh V. Ambudkar, and Susan E. Bates CHAPTER 13. Drug Transport in the Liver; Noora Sjöstedt, Jeffry Adiwidjaja, William A. Murphy, and Kim L.R. Brouwer CHAPTER 14. Drug Transport in the Brain; Vishal Sangha, Erica I. Williams, Patrick T. Ronaldson, and Reina Bendayan CHAPTER 15. Drug Transport in the Kidney; Douglas H. Sweet CHAPTER 16. Drug transporters in the human intestine; Stefan Oswald CHAPTER 17. Drug Transport in the Placenta; Qingcheng Mao, Vadivel Ganapathy, and Jashvant D. Unadkat CHAPTER 18. Polymorphisms of drug transporters and clinical relevance; Tore B. Stage and Deanna L. Kroetz CHAPTER 19. Ontogeny of Drug Transporters; Melanie A. Felmlee and Qing Zhang CHAPTER 20. Experimental Approaches for Studying Drug Transporters; Yusuke Masuo, Azusa Futatsugi, and Yukio Kato CHAPTER 21. Transporters mediated drug disposition – Physiochemistry and in silico approaches; Manthena V. S. Varma, Ayman El-Kattan, and Yurong Lai CHAPTER 22. In vitro-in vivo scale-up of drug transport activities; Kazuya Maeda and Yuichi Sugiyama CHAPTER 23. Application of Physiologically Based Pharmacokinetic and Pharmacodynamic (PBPK/PD) Modeling Comprising Transporters: Delineating the Role of Various Factors in Drug Disposition and Toxicity; Matthew D. Harwood, Amin Rostami-Hodjegan, and Sibylle Neuhoff CHAPTER 24. Transporters as therapeutic targets in human diseases; Robert S. Jones and Eugene C. Chen CHAPTER 25. Diet/Nutrient Interactions with Drug Transporters; Marilyn E. Morris and Tianjing Ren Index
• Edition: Third edition
• Publisher Details: Hoboken : John Wiley & Sons, Inc
• Publication Date: 2022
• Extent: 1 online resource
• Subjects: 572.69; Carrier proteins; Drug carriers (Pharmacy)
• Languages: English
• ISBNs: 9781119739876
• Related ISBNs: 9781119737551
• Notes: Note: Includes bibliographical references and index.; Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
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