Abnormal chromosomes : the past, present, and future of cancer cytogenetics /: the past, present, and future of cancer cytogenetics. (2022)

• Record Type: Book
• Further Information: Note: Felix Mitelman, Sverre Heim.
• Authors: Mitelman, Felix; Heim, Sverre
• Contents: Preface PART ONE: PAST Chapter 1 Understanding disease: ancient theories Chapter 2 The advent of cellular pathology Chapter 3 The colored bodies of cell nuclei: chromosomes and heredity Chapter 4 Boveri and the somatic mutation theory of cancer Chapter 5 Cytogenetics from 1914 to 1960: slow progress followed by serendipitous methodological breakthroughs leading to important discoveries Chapter 6 The first cancer-specific chromosome aberrations: Ph1 and others PART TWO: PRESENT Chapter 7 The banding revolution: cancer cytogenetics in the 1970s Chapter 8 Chasing correlations: chromosomes and oncogenes in leukemias and lymphomas Chapter 9 Solid tumor cytogenetics Chapter 10 Gains, losses, and rearrangements of genomic material: pathogenetic considerations Chapter 11 Morphology meets chemistry: integration of molecular genetics into the cytogenetic search for cancer-specific chromosome aberrations Chapter 12 Unravelling the clonal evolution of neoplastic cell populations Chapter 13 Clinical usefulness PART THREE: FUTURE Chapter 14 Toward a pathogenetic classification of cancer Chapter 15 Where there is structure, there is function Chapter 16 Which resolution level is optimally suited to answer which questions? Seeing never goes out of fashion… Chapter 17 Are new technological breakthroughs on the horizon? Afterthoughts Index
• Edition: 1st
• Publisher Details: Chichester : Wiley Blackwell
• Publication Date: 2022
• Extent: 1 online resource
• Subjects: 616.994042; Cancer -- Genetic aspects; Chromosome abnormalities; Cytogenetics
• Languages: English
• ISBNs: 9781119652052
• Related ISBNs: 9781119651987
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.