Cut-and-paste genetics : a CRISPR revolution /: a CRISPR revolution. (2021)

• Record Type: Book
• Further Information: Note: Sahotra Sarkar.
• Authors: Sarkar, Sahotra
• Contents: Preface 1.Breeding a Perfect Society Beginnings: Davenport and eugenics in the United States * IQ and involuntary sterilization * Genetics against eugenics * Exporting sterilization * The Watson scandal * Davenport’s dreams today 2.Molecular Diseases, Elusive Treatments The molecularization of biology * Molecular diseases * But no molecular medicine *Dreams of editing genes * Followed by stunning failure * Recombinant DNA made no difference * Gene editing BC 3.What Good Was the Human Genome Project? The sequence revealed * Common diseases and common variants * Medical irrelevance of the sequence * Critiques of the HGP, past and present * Evolution and architecture of the genome * Evolutionary contingency 4.The CRISPR Revolution The CRISPR structure emerges * Its function is decoded * The mechanism of immunity * Onward to gene editing * The delivery problem * Ubiquitous CRISPR 5.Inevitable Eugenics? Eugenics in the news * What is eugenics? * Defining eugenics * A working definition * Inescapable eugenics? * Matters of ethics 6.Eliminating Genetic Diseases The long reach of Huntington’s disease * The He Jiankui affair * The ethics of human germ-line intervention * The limits of current science * Gene specificity and Lenin’s brain * A policy proposal * Proceed with caution * Liberal and moderate eugenics 7.Designer Baby Delusions Why not genetic enhancement? * The normal and the enhanced * Liberal eugen- ics and genetic enhancement * Rationality of genetic enhancement * Planned human obsolescence * Where is the science? The case of intelligence * Genomics and IQ * What about physical traits * Genetic reductionism * Contextual developmental construction * What is perfection? 8.A CRISPR Future Editing the human germ-line * Gene drives * The ethics of promoting extinction *Biosecurity * CRISPR without the hype
• Publisher Details: Lanham : Rowman & Littlefield Publishers
• Publication Date: 2021
• Extent: 1 online resource, illustrations (black and white)
• Subjects: 576.5; Gene editing; Gene editing -- Moral and ethical aspects; CRISPR-associated protein 9
• Languages: English
• ISBNs: 9781786614391
• Related ISBNs: 9781786614377
• Notes: Note: Includes bibliographical references and index.; Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.