Tailor-made and functionalized biopolymer systems : for drug delivery and biomedical applications /: for drug delivery and biomedical applications. (2021)

• Record Type: Book
• Further Information: Note: Edited by Hriday Bera, Buddhadev Layek, Jagdish Singh.
• Editors: Bera, Hriday; Layek, Buddhadev; Singh, Jagdish
• Contents: List of contributors xv 1 Introduction to tailor-made biopolymers in drug delivery applications Yasir Faraz Abbasi, Parthasarathi Panda, Sanjay Arora, Buddhadev Layek and Hriday Bera 1.1 Introduction 1.2 Biopolymers from plant and animal kingdom 1.2.1 Polysaccharides 1.2.2 Polypeptides 1.2.3 Polynucleotides 1.3 Chemical modifications of biopolymers 1.3.1 Modification approaches of polysaccharides 1.3.2 Modification approaches of polypeptides 1.4 Tailor-made biopolymers as pharmaceutical excipients 1.5 Conclusion References Section 1 Modified biopolymers 2 Thiolated biopolymers in drug delivery and biomedical applications Custodiana A. Colmenarez Lobo, Mirta L. Fascio and Norma B. D’Accorso 2.1 Introduction 2.2 Thiolated biopolymers in drug delivery applications 2.3 Thiolated biopolymers in biomedical applications 2.3.1 Medicinal applications 2.3.2 Diagnosis 2.3.3 Regenerative medicine 2.4 Conclusion and future perspectives Acknowledgments References 3 Smart biopolymers for controlled drug delivery applications Sanjay Arora, Riddhi Trivedi, Richard N.L. Lamptey, Bivek Chaulagain, Buddhadev Layek and Jagdish Singh 3.1 Introduction 3.2 Different types of smart biopolymers 3.2.1 Thermosensitive smart polymers 3.2.2 pH-sensitive smart polymers 3.2.3 Light-sensitive smart polymers 3.2.4 Phase-sensitive smart polymers 3.2.5 Bioresponsive smart polymers 3.3 Conclusion References 4 Alginate-based systems for protein and peptide delivery Paramita Paul, Gouranga Nandi, Mohammed A. Abosheasha and Hriday Bera 4.1 Introduction 4.2 Alginate: sources, physicochemical and biological properties 4.2.1 Sources of alginates 4.2.2 Physicochemical properties 4.2.3 Biological properties 4.3 Modifications of alginate for protein and peptide delivery 4.3.1 Covalent chemical modifications 4.3.2 Polyelectrolyte complexes 4.4 Alginate-based systems for protein and peptide delivery 4.4.1 Model protein delivery 4.4.2 Insulin delivery 4.4.3 Angiogenic factor delivery 4.4.4 Chemokine delivery 4.4.5 Bone morphogenetic protein delivery 4.5 Conclusion References 5 Chitosan-based polyelectrolyte complexes in biomedical applications Buddhadev Layek, Surajit Das and Shubhajit Paul 5.1 Introduction 5.2 Polyelectrolyte complexes 5.2.1 Mechanism of polyelectrolyte complexes formation 5.2.2 Preparation of PECs and factors influencing the formation and stability of PECs 5.3 Applications of chitosan-based polyelectrolyte complexes 5.3.1 Drug delivery 5.3.2 Gene delivery 5.3.3 Tissue engineering 5.4 Conclusion References 6 Tailor-made cyclodextrin-based nanomaterials as drug carriers Kazi Ali, Pradyot Roy, Arindam Maity and Pranabesh Chakraborty 6.1 Introduction 6.1.1 History 6.1.2 Source of cyclodextrins 6.1.3 Types and structure of cyclodextrins 6.1.4 Properties of cyclodextrins 6.1.5 Inclusion complex formation 6.2 Modification of cyclodextrins 6.2.1 Principle and chemistry of cyclodextrin modification 6.2.2 Characterization of modified cyclodextrins 6.3 Cyclodextrin-based nanomaterials 6.3.1 Preparation of nanomaterials from cyclodextrins and applications 6.3.2 Different cyclodextrin-based nanomaterials 6.4 Pharmaceutical and biomedical applications of tailor-made CD-based nanomaterials 6.5 Conclusion and future prospects References Further reading Section 2 Biopolymeric conjugates/composites 7 Biopolymer_metal oxide composites in biomedical applications Yasir Faraz Abbasi and Hriday Bera 7.1 Introduction 7.2 Applications of biopolymer_metal oxide composites 7.2.1 Drug delivery 7.2.2 Anticancer, antioxidant, and antimicrobial activities 7.2.3 Wound healing and tissue engineering 7.2.4 Biosensors, bioimaging, and diagnostics 7.3 Conclusion References 8 Biopolymer_drug conjugates as biomaterials Haifei Guo, Yasir Faraz Abbasi, Hriday Bera and Mingshi Yang 8.1 Introduction 8.2 Biopolymer_drug conjugates 8.2.1 Polysaccharide-drug conjugates 8.2.2 Polypeptide_drug conjugates 8.3 Conclusion References 9 Functionalized biopolymer_clay-based composites as drug-cargos Hriday Bera, Motoki Ueda and Yoshihiro Ito 9.1 Introduction 9.2 Structure and properties of clays 9.3 Biopolymer_clay intercalations 9.4 Properties of biopolymer_clay-based composites as drug-delivery systems 9.4.1 Improvement of clay properties 9.4.2 Improvement of polymer properties 9.5 Biopolymer_clay-based composites as drug-delivery systems 9.5.1 Animal-derived polysaccharide_clay composites 9.5.2 Algae-derived polysaccharide_clay composites 9.5.3 Plant-derived polysaccharide_clay composites 9.5.4 Natural protein_clay composites 9.5.5 Biopolymer blend_clay composites 9.6 Conclusion References 10 Mesoporous silica-biopolymer-based systems in drug delivery applications Suman Saha, Payal Roy and Jui Chakraborty 10.1 Introduction 10.2 Classification of MSNs, their structures and properties 10.2.1 Two-dimensional mesostructures 10.2.2 Three-dimensional mesostructures 10.2.3 Classification of mesoporous silica nanoparticles as drug carriers 10.3 Different synthesis techniques of mesoporous silica nanoparticles 10.3.1 Hydrothermal synthesis 10.3.2 Aerosol-assisted synthesis 10.3.3 Modified St&e_004E7;ber’s synthesis 10.3.4 Template-assisted synthesis 10.3.5 Microwave synthesis 10.3.6 Chemical etching synthesis 10.4 Functionalization of mesoporous silica nanoparticles using synthetic polymers/biopolymers 10.4.1 Functionalization techniques 10.5 Different biopolymer-MSN systems in drug delivery applications 10.5.1 Drug delivery for cancer treatment 10.5.2 Drug delivery for other disease treatment 10.5.3 Gene delivery 10.5.4 Drug delivery and bioimaging 10.6 Stability and degradation profiles 10.7 Biocompatibility, pharmacology, and toxicological profiles 10.8 Conclusion, challenges, and future prospects Acknowledgments References Section 3 Modified biopolymer based biomaterials 11 Micellar drug-delivery systems based on amphiphilic block and graft polysaccharides Leonard Ionut Atanase 11.1 Introduction 11.2 Micellization and drug-loading methods 11.3 Characterization techniques of drug-free and drug-loaded micellar systems 11.4 Polysaccharide-based micellar drug-delivery systems 11.4.1 Chitosan-based micellar drug-delivery systems 11.4.2 Cellulose-based micellar drug-delivery systems 11.4.3 Dextran-based micellar drug-delivery systems 11.4.4 Starch-based micellar drug-delivery systems 11.4.5 Alginate-based micellar drug-delivery systems 11.4.6 Hyaluronic acid_based micellar drug-delivery systems 11.4.7 Miscellaneous polysaccharide-based micellar drug-delivery systems
• Publisher Details: Oxford : Woodhead Publishing
• Publication Date: 2021
• Extent: 1 online resource, illustrations (black and white, and colour)
• Subjects: 572.33; Biopolymers -- Therapeutic use; Drug delivery systems; Biomedical materials
• Languages: English
• ISBNs: 9780128214572
• Related ISBNs: 9780128214374
• Notes: Note: Description based on CIP data; resource not viewed.
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