Cardiac Gene Therapy : Methods and Protocols /: Methods and Protocols. (2016)

• Record Type: Book
• Further Information: Note: Kiyotake Ishikawa.
• Editors: Ishikawa, Kiyotake
• Contents: Part I: Overview 1. Current Methods in Cardiac Gene Therapy: Overview Kiyotake Ishikawa and Roger J. Hajjar Part II: Genetic Modification 2. Silencing Genes in the Heart Henry Fechner, Roland Vetter, Jens Kurreck, and Wolfgang Poller 3. Generation of Efficient miRNA Inhibitors Using Tough Decoy Constructs Jimeen Yoo, Roger J. Hajjar, and Dongtak Jeong 4. Efficient Genome Editing in Induced Pluripotent Stem Cells with Engineered Nucleases In Vitro Vittavat Termglinchan, Timon Seeger, Caressa Chen, Joseph C. Wu, and Ioannis Karakikes 5. Direct Cardiac Reprogramming as a Novel Therapeutic Strategy for Treatment of Myocardial Infarction Hong Ma, Li Wang, Jiandong Liu, and Li Qian Part III: Gene Delivery Vectors 6. Production and Characterization of Vectors Based on the Cardiotropic AAV Serotype 9 Erik Kohlbrenner and Thomas Weber 7. Cell-Based Measurement of Neutralizing Antibodies Against Adeno-Associated Virus (AAV) Andreas Jungmann, Oliver Müller, and Kleopatra Rapti 8. Synthesis of Modified mRNA for Myocardial Delivery Jason Kondrat, Nishat Sultana, and Lior Zangi 9. Exosomes-Based Gene Therapy for MicroRNA Delivery Prabhu Mathiyalagan and Susmita Sahoo 10. Lipidoid mRNA Nanoparticles for Myocardial Delivery in Rodents Irene C. Turnbull, Ahmed A. Eltoukhy, Daniel G. Anderson, and Kevin D. Costa Part IV: Gene Delivery Methods 11. Gene Transfer in Isolated Adult Cardiomyocytes Kjetil Hodne, David B. Lipsett, and William E. Louch 12. Gene Transfer in Cardiomyocytes Derived from ES and iPS Cells Francesca Stillitano, Ioannis Karakikes, and Roger J. Hajjar 13. Gene Transfer to Rodent Hearts In Vivo Federica del Monte, Kiyotake Ishikawa, and Roger J. Hajjar 14. Ultrasound-Targeted Microbubble Destruction for Cardiac Gene Delivery Shuyuan Chen and Paul A. Grayburn 15. A Needleless Liquid Jet Injection Delivery Approach for Cardiac Gene Therapy Anthony S. Fargnoli, Michael G. Katz, and Charles R. Bridges 16. Cardiac Gene Delivery in Large Animal Models: Antegrade Techniques Shin Watanabe, Lauren Leonardson, Roger J. Hajjar, and Kiyotake Ishikawa 17. Direct Myocardial Injection of Vectors Guillaume Bonnet, Kiyotake Ishikawa, Roger J. Hajjar, and Yoshiaki Kawase 18. Selective Pressure-Regulate Retroinfusion for Gene Therapy Application in Ischemic Heart Disease Rabea Hinkel and Christian Kupatt 19. Cardiac Gene Delivery Using Recirculating Devices Melissa J. Byrne and David M. Kaye 20. Molecular Cardiac Surgery with Recirculating Delivery (MCARD): Procedure and Vector Transfer Michael G. Katz, Anthony S. Fargnoli, Andrew P. Kendle, and Charles R. Bridges Part V: Targeting Arrhythmia 21. Gene Delivery for the Generation of Bioartificial Pacemaker Patrick K.W. Chan and Ronald A. Li 22. Gene Therapy for Post-Infarction Ventricular Tachycardia J. Kevin Donahue Part VI: Targeting Pulmonary Hypertension 23. MicroRNA Delivery Strategies to the Lung in a Model of Pulmonary Hypertension Lin Deng, Andrew H. Baker, and Angela C. Bradshaw 24. Inhaled Gene Transfer for Pulmonary Circulation Jaume Aguero, Lahouaria Hadri, Nadjib Hammoudi, Lauren Leonardson, Roger J. Hajjar, and Kiyotake Ishikawa.
• Publisher Details: New York : Humana Press
• Publication Date: 2016
• Copyright Date: 2017
• Extent: 1 online resource (355 pages)
• Subjects: Medicine; Science -- Life Sciences -- Biology -- Molecular Biology; Medical research
• Languages: English
• ISBNs: 9781493965885
• Related ISBNs: 9781493965861
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.