Epigenetics in cardiovascular disease. (2021)

• Record Type: Book
• Further Information: Note: Edited by Yvan Devaux, Emma Louise Robinson.
• Editors: Devaux, Yvan; Robinson, Emma Louise
• Contents: Section I: Introductory information 1. The ever-growing burden of cardiovascular disease 2. Epigenetics concepts - an overview 3. From classical signalling pathway to the nucleus Section II: Epigenetics mechanisms in cardiovascular disease 4. DNA methylation in cardiovascular disease development 5. Histone modifications in cardiovascular disease initiation and progression 6. Post transcriptional RNA modifications in cardiovascular disease 7. Regulatory RNAs in cardiovascular disease 8. Regulation of splicing in cardiovascular disease 9. Cardiac Transcriptomic Remodelling in Metabolic Syndrome 10. Sex differences in epigenetics mechanisms of cardiovascular disease 11. Epigenetics of cardiac development and iPS cells Section III: Biomarker value 12. Peripheral Blood DNA and RNA Biomarkers of Cardiovascular Disease in Clinical Practice 13. Epigenetics and physical exercise 14. Long non-coding RNAs and circular RNAs as heart failure biomarkers 15. Artificial intelligence in clinical decision-making for diagnosis of cardiovascular disease Section IV: Therapeutic potential 16. Therapeutic strategies for modulating epigenetic mechanisms in cardiovascular disease Section V: Methodological issues 17. RNA-sequencing and single cell RNA-seq in cardiovascular medicine 18. Good laboratory and experimental practices for microRNA analysis in cardiovascular research 19. Analytical challenges in microRNA biomarker development - Best practices for analyzing microRNAs in cell-free biofluids 20. Concept of biological reference materials for RNA analysis in cardiovascular disease 21. Unbiased bioinformatics analysis of microRNA transcriptomics datasets and network theoretic target prediction
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2021
• Extent: 1 online resource
• Subjects: 616.1; Cardiovascular system -- Diseases; Epigenetics
• Languages: English
• ISBNs: 9780128222591
• Related ISBNs: 9780128222584
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.