The design and development of novel drugs and vaccines : principles and protocols /: principles and protocols. (2021)

• Record Type: Book
• Further Information: Note: Edited by Tarun Kumar Bhatt, Surendra Nimesh.
• Editors: Bhatt, Tarun Kumar; Nimesh, Surendra
• Contents: 1. Introduction of structural bioinformatics with respect to drug discovery 2. Target identification and validation 3. Retrieval of compounds 4. Lead identification and optimization 5. Molecular dynamics simulations 6. An overview of vaccine design 7. Key steps in the selection of vaccine targets 8. Epitope prediction and selection of linkers and adjuvant 9. Design of vaccine constructs 10. In-silico validation through protein-protein docking 11. Molecular cloning 12. Protein expression 13. Protein purification and desalting 14. Biological assay 15. Biophysical methods 16. Outline of animal study for lead/ vaccine testing 17. Evaluation of immunogenicity of vaccine candidate 18. In-vitro evaluation of lead molecule 19. Medical physiological parameter for lead/vaccine testing 20. Brief introduction of clinical research and trials 21. An overview of IND, NDA, approval agencies and FDA post-marketing surveillance 22. Introduction of Intellectual property rights
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2021
• Extent: 1 online resource
• Subjects: 615.1900721; Drug development -- Methodology; Vaccines -- Research -- Methodology
• Languages: English
• ISBNs: 9780128214756
• Related ISBNs: 9780128214718
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.