Computational genomics with R. (2020)

• Record Type: Book
• Further Information: Note: Altuna Akalin.
• Authors: Akalin, Altuna
• Contents: 1. Introduction to Genomics ; Genes, DNA and central dogma What is a genome? What is a gene? How genes are controlled? The transcriptional and the post-transcriptional regulation What does a gene look like? Elements of gene regulation Transcriptional regulation Post-transcriptional regulation Shaping the genome: DNA mutation High-throughput experimental methods in genomics The general idea behind high-throughput techniques High-throughput sequencing Visualization and data repositories for genomics 2. Introduction to R for Genomic Data Analysis ; Steps of (genomic) data analysis Data collection Data quality check and cleaning Data processing Exploratory data analysis and modeling Visualization and reporting Why use R for genomics ? Getting started with R Installing packages Installing packages in custom locations Getting help on functions and packages Computations in R Data structures ; Vectors Matrices Data Frames Lists Factors Data types Reading and writing data Reading large files Plotting in R with base graphics Combining multiple plots Saving plots Plotting in R with ggplot Combining multiple plots ggplot and tidyverse Functions and control structures (for, if/else etc) User defined functions &nb
• Edition: 1st
• Publisher Details: Boca Raton : Chapman & Hall/CRC
• Publication Date: 2020
• Extent: 1 online resource, illustrations
• Subjects: 572.860285; Genomics -- Data processing; Computational biology; Bioinformatics -- Computer simulation; R (Computer program language)
• Languages: English
• ISBNs: 9780429532764; 9781498781862; 9780429547461; 9780429084317
• Related ISBNs: 9781498781855
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.