Rosacea. ([2020])

• Record Type: Book
• Further Information: Note: John Havens Cary, Howard I. Maibach, editors.
• Editors: Cary, John Havens; Maibach, Howard I
• Contents: Intro -- Preface -- Contents -- Contributors -- 1: Introduction to Clinical Rosacea -- Rosacea Is a Syndrome and Not a Pathogenically Defined Disease -- History of Classification of Rosacea: Distinction from Acne and Recognition of Phenotypic Subtypes -- The Four Classic Phenotypic Subtypes of Rosacea Have Important Utilities -- The Flawed Proposal to Eliminate the Classic Phenotypic Subtypes -- The Classic Phenotypic Subtypes Are Useful and Will Persist -- Incidence -- History -- History of Present Illness -- Past Medical History -- Medication History -- Family History -- Social History Review of Systems -- Physical Exam -- Differential Diagnoses -- Histology -- References -- 2: Pathophysiology of Rosacea -- Introduction -- Current Concepts of the Pathophysiology -- Genes in Rosacea -- Innate Immunity and Adaptive Immunity -- Neuroimmune and Neurovascular Dysregulation -- Novel Insights and Promising Targets -- Future Studies -- Conclusion -- References -- 3: Genetics of Rosacea -- Background -- Epidemiology -- Familial Inheritance Studies -- Twin Concordance Studies -- Gene Association Case-Control Studies -- Molecular and Functional Data -- Endoplasmic Reticulum (ER) Stress Toll-Like Receptor (TLR)-2 -- Antimicrobial Peptides -- Transient Receptor Potential Vanilloid 1 (TRPV1) -- Neurovascular Factors -- Mast Cells -- IL-17 -- TSLP -- Associations with Comorbidities -- Conclusion and Future Directions -- References -- 4: Evidence-Based Management -- Introduction -- Environmental Modification -- Topical Therapies -- Metronidazole -- Azelaic Acid -- Sodium Sulfacetamide-Sulfur -- Calcineurin Inhibitors -- Crotamiton, Ivermectin, and Permethrin -- Clindamycin -- Retinoids -- Systemic Therapies -- Doxycycline and Minocycline -- Macrolides -- Antihypertensives Isotretinoin -- Conclusion -- References -- 5: Difference in Vasoconstrictors: Oxymetazoline Versus Brimonidine -- Introduction -- Vascular Anatomy -- Brimonidine -- Pharmacodynamics and Pharmacokinetics -- Administration and Interactions -- Indication and Clinical Management -- Efficacy -- Adverse Effects -- Oxymetazoline -- Pharmacodynamics and Pharmacokinetics -- Administration and Interactions -- Indication and Clinical Management -- Efficacy -- Adverse Effects -- Oxymetazoline Versus Brimonidine -- Conclusion -- References -- 6: Treatment of Ocular Rosacea -- Introduction Conservative Therapy -- Topical Medical Therapy -- Systemic Therapy -- Procedural and Surgical Therapy -- Future Directions -- Conclusion -- References -- 7: Physical Modalities for the Treatment of Rosacea -- Introduction -- Light and Laser Applications for Vascular Lesions -- Pulsed Dye Laser (PDL) -- KTP Laser -- Long-Pulsed Nd:YAG Laser -- Intense Pulse Light (IPL) -- Summary: Therapy of Vascular Lesions -- Physical Therapeutic Options in the Treatment of Phymatous Rosacea Manifestations -- Dermashaving (Scalpel) -- Dermabrasion -- Electrosurgery (Fig. 7.1a-c) -- Laser Surgery (Fig. 7.2a, b)
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2020
• Extent: 1 online resource
• Subjects: 616.5/3; Rosacea; Electronic books
• Languages: English
• ISBNs: 9783030520977; 3030520978
• Related ISBNs: 303052096X; 9783030520960
• Notes: Note: Includes bibliographical references and index.; Note: Description based on online resource; title from digital title page (viewed on November 02, 2020).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.