Ribozymes. (2020)

• Record Type: Book
• Further Information: Note: Edited by Sabine Müller, Benoît Masquida, Wade Winkler.
• Editors: Müller, Sabine, 1954-; Masquida, Benoît; Winkler, Wade C, 1972-
• Contents: INTRODUCTION; The chemical principles of RNA catalysis; ; NATURALLY OCCURRING RIBOZYMES; Biological roles of self-cleaving ribozymes; Chemical mechanisms of the nucleolytic ribozymes; The glmS ribozyme and its multifunctional coenzyme glucosamine-6-phosphate; The lariat capping ribozyme; Self-splicing group II introns; The Spliceosome: an RNA-Protein ribozyme derived from ancient mobile genetic elements; The ribosome and protein synthesis; The RNase P ribozyme; Ribozyme Discovery in Bacteria; Small self-cleaving ribozymes in the genomes of vertebrates; ; ENGINEERED RIBOZYMES; Phosphoryl transfer ribozymes; RNA replication and the RNA polymerase ribozyme; Maintenance of genetic information in the first ribocell; Ribozyme-catalyzed RNA recombination; Engineering of hairpin ribozymes for RNA processing reactions; Engineering of the Neurospora Varkud Satellite ribozyme for cleavage of non-natural stem-loop substrates; Chemical modifications in natural and engineered ribozymes; Ribozymes for regulation of gene expression; Development of flexizyme aminoacylation ribozymes and their applications; In vitro selected (deoxy)ribozymes that catalyze carbon-carbon-bond formation; Nucleic acid catalyzed RNA ligation and labeling; ; DNAZYMES; The chemical repertoire of DNA enzymes; Light-utilizing DNAzymes; Applications of DNAzymes in computing and nanotechnology; ; RIBOZYMES AS TOOLS IN DIAGNOSTICS AND THERAPY; Optimization of antiviral ribozymes; DNAzymes as Biosensors; Compartmentalization-based technologies for in vitro selection and evolution of ribozymes and light-up RNA aptamers; ; TOOLS AND METHODS TO STUDY RIBOZYMES; Elucidation of ribozyme mechanisms at the example of the Pistol ribozyme; Strategies for crystallization of natural ribozymes; NMR spectroscopic investigation of ribozymes; Studying Ribozymes with Electron Paramagnetic Resonance Spectroscopy; Computational modeling methods for 3D structure prediction of ribozymes
• Edition: 1st
• Publisher Details: Weinheim : Wiley-VCH
• Publication Date: 2020
• Extent: 1 online resource
• Subjects: 572.88; Catalytic RNA; Genetic regulation
• Languages: English
• ISBNs: 9783527814534; 9783527814558
• Related ISBNs: 9783527344543
• Notes: Note: Description based on CIP data; resource not viewed.
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• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.