Translational bioinformatics for therapeutic development. ([2021])

• Record Type: Book
• Further Information: Note: Edited by Joseph Markowitz.
• Other Names: Markowitz, Joseph
• Contents: 1. Development and Optimization of Clinical Informatics Infrastructure to Support Bioinformatics at an Oncology Center Randa M. Perkins and Joseph Markowitz 2. Leveraging Pathology Informatics Concepts to Achieve Discrete Lab Data for Clinical Use and Translational Research Mandy Flannery O'Leary 3. Cohort Identification for Translational Bioinformatics Studies Tiffany A. Lin, Zeynep Eroglu, Rodrigo Carvajal, and Joseph Markowitz 4. Transitioning Clinical Practice Guidelines into the Electronic Health Record through Clinical Pathways Sharjeel M. Hooda and Karen K. Fields 5. Variable Selection for Time-to-Event Data Ai Ni and Chi Song 6. Binary Classification for Failure Risk Assessment Ali Foroughi pour, Ian Loveless, Grzegorz Rempala and Maciej Pietrzak 7. Challenges and Opportunities of Genomic Approaches in Therapeutics Development Jaimie S. Gray and Moray J. Campbell 8. Accessible Pipeline for Translational Research using TCGA: Examples of Relating Gene Mechanism to Disease Specific Outcomes Anders E. Berglund, Ryan M Putney, Jordan H. Creed, Garrick Aden-Buie, Travis A. Gerke, and Robert J. Rounbehler 9. Statistical and Bioinformatics Analysis of Data from Bulk and Single-Cell RNA Sequencing Experiments Xiaoqing Yu, Farnoosh Abbas-Aghababazadeh, Y. Ann Chen, and Brooke L. Fridley 10. Investigating Inter- and Intra-Sample Diversity of Single-Cell RNA Sequencing Datasets Meghan C. Ferrall-Fairbanks and Philipp M. Altrock 11. Managing a Large-scale Multi-Omics Project: A Team Science Case Study in Proteogenomics Paul A. Stewart, Eric A. Welsh, Bin Fang, Victoria Izumi, Tania Mesa, Chaomei Zhang, Sean Yoder, Guolin Zhang, Ling Cen, Fredrik Pettersson, Yonghong Zhang, Zhihua Chen, Chia-Ho Cheng, Ram Thapa, Zachary Thompson, Melissa Avedon, Marek Wloch, Michelle Fournier, Katherine M. Fellows, Jewel M. Francis, James J. Saller, Theresa A. Boyle, Y. Ann Chen, Eric B. Haura, Jamie K. Teer, Steven A. Eschrich, and John M. Koomen 12. Synergistic Drug Combination Prediction by Integrating Multi-omics Data in Deep Learning Models Tianyu Zhang, Liwei Zhang, Philip R.O. Payne, and Fuhai Li 13. Introduction to Multi-Parametric Flow Cytometry and Analysis of High-Dimensional Data James Sun, Jodi L. Kroeger, and Joseph Markowitz 14. High Dimensional Flow Cytometry Analysis of Regulatory Receptors on Human T cells, NK cells, and NKT Cells* Ryosuke Nakagawa, Jason Brayer, Nicole Restrepo, James J. Mulé, and Adam W Mailloux 15. Quantitative Analysis of Bile Acid with UHPLC-MS/MS Yuan Tian, Jingwei Cai, Erik L. Allman, Philip B. Smith, and Andrew D. Patterson 16. Sample Preparation and Data Analysis for NMR–based Metabolomics Tapas K. Mal, Yuan Tian, and Andrew D. Patterson.
• Publisher Details: New York, NY : Humana Press
• Publication Date: 2021
• Extent: 1 online resource
• Subjects: 570.285; Bioinformatics -- Laboratory manuals; Molecular biology; Science -- Life Sciences -- Anatomy & Physiology; Electronic books
• Languages: English
• ISBNs: 9781071608494; 1071608495
• Related ISBNs: 1071608487; 9781071608487
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed November 11, 2020).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.