Clinical bioenergetics : from pathophysiology to clinical translation /: from pathophysiology to clinical translation. (2020)

• Record Type: Book
• Further Information: Note: Edited by Sergej M. Ostojic.
• Editors: Ostojic, Sergej M
• Contents: Part 1: Foundational Aspects of Bioenergetics and Disease 1. Tissue specificity of energy metabolism in mitochondria 2. Sex hormones, tissue bioenergetics and metabolism in humans 3. Impaired mitochondrial bioenergetics and signalling pathways: an overview Part 2: Disease-Specific Case Studies 4. Abnormal mitochondrial metabolism in obesity and insulin resistance 5. Impaired mitochondrial energy metabolism: Etiologies and implications in neurodegenerative disease 6. Mitochondrial dysfunction and kidney disease 7. Role of mitochondria in non-alcoholic liver disease as a chronic disorder 8. Decreased bioenergetics in traumatic brain injury 9. Impaired mitochondrial bioenergetics in psychiatric disorders 10. Mitochondrial dysfunction and impaired bioenergetics of pulmonary fibrosis 11. Mitochondrial dysfunction and impaired bioenergetics in skin diseases Part 3: Modes of Analysis in Clinical Bioenergetics 12. Monitoring mitochondrial oxygenation in clinical environment 13. Assessing metabolic flexibility and mitochondrial bioenergetics 14. Assessing the real-time metabolism and bioenergetics of single cells using fluorescence biosensors 15. Blood-based bioenergetic profiling in clinical environment 16. Bioenergetic profiling in the skin 17. Evaluating tissue bioenergetics via magnetic resonance spectroscopy 18. Targeting respiratory complex I – molecular mechanism and drug design Part 4: Theraputic Opportunities for Impaired Bioenergetics 19. Models for target effects of drugs on mitochondrial bioenergetics 20. Gene therapy for impaired mitochondrial bioenergetics 21. Mitochondria replacement as an innovative treatment to tackle impaired bioenergetics in clinical medicine 22. Mitochondrial drug delivery systems: therapeutic applications for clinical bioenergetics 23. Dietary interventions for patients with obesity and impaired bioenergetics 24. Novel nutraceuticals to tackle brain and muscle bioenergetics 25. Therapeutic potential of cardiolipin-protective compound to restore mitochondrial bioenergetics 26. NEET proteins as novel drug targets for mitochondrial dysfunction 27. Translation of bioenergetics therapies: challenges from bench to bedside 28. New therapeutics to modulate mitochondrial energy metabolism in neurodegenerative disorders 29. Targeting impaired bioenergetics in heart failure 30. Pharmacological targeting of mitochondria in cancer 31. Modulation of the mitochondrial function with natural bioactive compounds to treat obesity and insulin resistance 32. Antioxidants and natural derived products in the modulation of Mt bioenergetic dysfunction in chronic kidney disease 33. Transcranial and systemic photobiomodulation for the enhancement of mitochondrial metabolism in depression 34. Impairments in oxidative glucose metabolism in epilepsy and advanced metabolic treatments: an overview
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2020
• Extent: 1 online resource
• Subjects: 612.01421; Bioenergetics; Clinical biochemistry
• Languages: English
• ISBNs: 9780128227725
• Related ISBNs: 9780128196212
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
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