PH-interfering agents as chemosensitizers in cancer therapy. (2020)

• Record Type: Book
• Further Information: Note: Edited by Claudiu Supuran, Simone Carradori.
• Editors: Supuran, Claudiu T, 1962-; Carradori, Simone
• Contents: PART I General overview of the topic: An update 1. General introduction about general mechanisms of resistance in cancer (hypoxia, efflux pumps, tumoral microenvironment) and use of chemosensitizers in association with drugs already in the market 2. Clinical studies analysis 3. Combination therapy 4. Oncoimmunology PART II Chemosensitizing agents with a validated mechanism of action 5. pH regulators of the tumoral microenvironment 6. Proton Pump Inhibitors (PPIs) and other pH buffering agents 7. Selective hCA IX and XII inhibitors 8. Epigenetic modulators 9. Photosensitizing agents 10. Efflux pumps and ABC transporter subfamily inhibitors (e.g., cyclosporin A, verapamil) 11. Metalloproteinase inhibitors (e.g., ADAM17) 12. Kinesin inhibitors 13. Drug repurposing 14. Innovative and putative targets for chemosensitizers 15. Patent survey on chemosensitizers PART III Chemosensitizing agents from natural sources 16. Natural compounds as chemosensitizers: a lesson from plants 17. Natural compounds: from food to clinic PART IV Chemosensitizing agents: Computational tools and technological approaches 18. Virtual screening and chemoinformatics of new library of chemosensitizers 19. Nanostructures overcoming cancer resistance
• Publisher Details: Amsterdam : Academic Press
• Publication Date: 2020
• Extent: 1 online resource
• Subjects: 616.994061; Cancer -- Chemotherapy; Cancer -- Treatment -- Technological innovations
• Languages: English
• ISBNs: 9780128209288
• Related ISBNs: 9780128207017
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.