Lipid transfer in lipoprotein metabolism and cardiovascular disease. (2020)

• Record Type: Book
• Further Information: Note: Xian-Cheng Jiang, editor.
• Other Names: Jiang, Xian-Cheng
• Contents: Intro -- Preface -- Contents -- Chapter 1: Impact of Phospholipid Transfer Protein in Lipid Metabolism and Cardiovascular Diseases -- 1.1 Phospholipid Transfer Protein (PLTP) -- 1.2 PLTP and Cholesteryl Ester Transfer Protein (CETP) -- 1.3 Regulation of PLTP -- 1.4 PLTP and HDL -- 1.5 PLTP and Reverse Cholesterol Transport (RCT) -- 1.6 PLTP and ApoB-Containing-Triglyceride-Rich Lipoprotein (BLp) Secretion -- 1.7 PLTP and Obesity/Insulin Resistance -- 1.8 PLTP and Thrombosis -- 1.9 PLTP and Inflammation -- 1.10 PLTP and Cardiovascular Diseases -- 1.11 Conclusion -- References Chapter 2: Cholesteryl Ester Transfer Protein and Lipid Metabolism and Cardiovascular Diseases -- 2.1 Introduction -- 2.2 Reverse Cholesterol Transport -- 2.3 Human Genetic Studies -- 2.4 Possible New Function of CETP: Anti-inflammatory -- 2.5 Does CETP Have an Intracellular Function? -- 2.6 CETP Inhibition as a Target to Decrease Cardiovascular Diseases -- Box 2.1 Main CETP Inhibitor Trials -- 2.6.1 Torcetrapib -- 2.6.2 Dalcetrapib -- 2.6.3 Evacetrapib -- 2.6.4 Anacetrapib -- 2.6.5 TA-8995 (Obicetrapib) -- 2.7 Concluding Remarks -- References Chapter 3: Lipopolysaccharide-Binding Protein and Bactericidal/Permeability-Increasing Protein in Lipid Metabolism and Cardiov... -- 3.1 The Gene Loci and Expression of BPI and LBP -- 3.2 Structures and Functions of LBP and BPI -- 3.3 LBP and BPI in Lipid Metabolism and Cardiovascular Research -- 3.3.1 LBP -- 3.3.2 BPI -- References -- Chapter 4: Microsomal Triglyceride Transfer Protein: From Lipid Metabolism to Metabolic Diseases -- 4.1 Introduction -- 4.2 Role of Microsomal Triglyceride Transfer Protein in Lipid and Lipoprotein Metabolism 4.3 Regulation of Microsomal Triglyceride Transfer Protein -- 4.4 Lipids and Lipoproteins in Metabolic Syndrome -- 4.5 Therapeutic Intervention of MTP to Alleviate Dyslipidemia in Metabolic Syndrome -- 4.6 Conclusions -- References -- Chapter 5: Circadian Clock Regulation on Lipid Metabolism and Metabolic Diseases -- 5.1 Introduction -- 5.2 Origins of the Mammalian Clock -- 5.3 Physiological Functions of Circadian Clock -- 5.4 Preclinical Studies on Diurnal Rhythm in Phospholipid Metabolism -- 5.5 Clinical Studies on Circadian Clocks ́Role in Phospholipid Metabolism -- 5.6 Conclusion
• Publisher Details: Singapore : Springer
• Publication Date: 2020
• Extent: 1 online resource (235 p.)
• Subjects: 572/.574; Lipids -- Metabolism; Lipoproteins; Electronic books; Electronic books
• Languages: English
• ISBNs: 9789811560828
• Related ISBNs: 981156082X; 9811560811; 9789811560811
• Notes: Note: References -- Chapter 6: ABC Transporters, Cholesterol Efflux, and Implications for Cardiovascular Diseases -- 6.1 Introduction -- 6.2 ABC Transporters and Cholesterol Efflux -- 6.3 Mechanisms Underlying ABC Transporter-Mediated Cholesterol Efflux -- 6.4 Regulation of ABC Transporters -- 6.5 ABC Transporters in HDL Metabolism and ACD -- 6.6 ABCA1- and ABCG1-Mediated Cholesterol Efflux Pathways in Inflammation and Atherogenesis -- 6.7 Abca1- and Abcg1-Mediated Cholesterol Efflux Suppress Monocytosis and Neutrophilia
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