Pathology of peritoneal metastases the unchartered fields /: the unchartered fields. (2020)

• Record Type: Book
• Further Information: Note: Olivier Glehen, Aditi Bhatt, editors.
• Other Names: Glehen, Olivier; Bhatt, Aditi
• Contents: Intro -- Preface -- Contents -- About the Editors -- 1: Mechanisms of Peritoneal Metastasis Formation -- 1.1 Introduction -- 1.2 Mechanisms of Trans-mesothelial Metastasis -- 1.2.1 Mechanisms of Cancer Cell Spillage into the Peritoneal Cavity -- 1.2.2 Adhesion of PFCCs and Mesothelial Cells (Fig. 1.1, Process 1) -- 1.2.3 Morphological Changes of Mesothelial Cells (Fig. 1.1, Process 1), Submesothelial Invasion of PFCCs, Attachment of PFCCs to the Basement Membrane (Fig. 1.1, Process 2) -- 1.2.4 Adhesion of PFCCS to the Submesothelial Basement Membrane (Fig. 1.1, Process 2 and Fig. 1.6) 1.2.5 Invasion into the Submesothelial Tissue (Fig. 1.1, Process 3) -- 1.2.6 Destruction of Submesothelial Basement Membrane and Extracellular Matrix (ECM) and Invasion into Submesothelial Tissue (Fig. 1.1, Process 3) -- 1.2.7 Proliferation in the Subperitoneal Tissue (Fig. 1.1, Process 4: Angiogenesis and Proliferation) -- 1.3 Trans-lymphatic Metastasis -- 1.4 Mechanisms of Superficial Growing Metastasis -- References -- 2: Extent of Peritoneal Resection for Peritoneal Metastases: Inferences from Pathophysiology -- 2.1 Background and Introduction 2.1.1 Evolution of Peritoneal Surface Oncology -- 2.2 Pathophysiology of Peritoneal Metastases and Its Clinical Implications -- 2.2.1 Peritoneal Metastatic Cascade -- 2.2.2 Distribution of Disease in the Peritoneal Cavity -- 2.2.2.1 Epithelial Ovarian Cancer -- 2.2.3 Implications of Mechanism of Peritoneal Dissemination on Surgical Resection -- 2.2.4 Morphology of Peritoneal Deposits and Morphological Evolution of Peritoneal Metastases -- 2.2.4.1 Morphological Evolution of PM -- 2.2.4.2 Alteration in Morphology After Systemic Chemotherapy -- 2.2.4.3 Histological Subtype 2.2.5 Impact on the Extent of Surgical Resection -- 2.2.6 Resection of Uninvolved Regions -- 2.2.7 Primary Tumor Type -- 2.2.8 Lymphadenectomy in Addition to Cytoreductive Surgery -- 2.2.9 Prognostic Implications of Lymph Node Involvement -- 2.3 Extent of Peritoneal Resection for PM Arising from Various Primary Tumors -- 2.3.1 Studies Looking at the Extent of Peritoneal Resection -- 2.3.2 Application in Clinical Practice and Question for Future Research -- 2.4 Conclusions -- References -- 3: Therapeutic Rationale and Data Set for Reporting Cytoreductive Surgery Specimens 3.1 Introduction -- 3.2 Anatomical Considerations -- 3.2.1 Peritoneal Regions -- 3.2.2 Lymphatic Drainage -- 3.2.3 Subperitoneal Nodes -- 3.2.4 Omental Nodes -- 3.2.5 Retroperitoneal Nodes -- 3.2.6 Paracardiac and Mediastinal Nodes -- 3.3 Pathological Evaluation of Cytoreductive Surgery Specimens -- 3.3.1 The Surgeon's Role -- 3.3.1.1 Labelling of Surgical Specimens by the Surgeon -- 3.3.1.2 Morphological Description -- 3.3.2 The Pathologist's Role -- 3.3.2.1 Handling of Specimens by the Pathologist -- 3.3.2.2 Gross Description and Sectioning -- Peritonectomy Specimen(s)
• Publisher Details: Singapore : Springer
• Publication Date: 2020
• Extent: 1 online resource
• Subjects: 616.99/495; Peritoneum -- Cancer; Peritoneum -- Cancer; Electronic books; Electronic books
• Languages: English
• ISBNs: 9789811537738; 9811537739
• Related ISBNs: 9811537720; 9789811537721
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.