Epigenetics in allergy and autoimmunity. (2020)

• Record Type: Book
• Further Information: Note: Christopher Chang, Qianjin Lu, editors.
• Other Names: Chang, Christopher C; (Professor of dermatology), Lu, Qianjin
• Contents: Intro -- Preface -- Contents -- Editors and Contributors -- Part I Introduction -- 1 Epigenetics in Health and Disease -- 1.1 Introduction -- 1.2 The Science Behind Epigenetics -- 1.3 Epigenetics and Human Disease -- 1.4 The Clinical Application of Epigenetics -- 1.4.1 Epigenetic Biomarkers -- 1.4.2 Epigenetic Therapy -- 1.5 Epigenetic in Diseases -- 1.5.1 The Role of Epigenetics in Cancer -- 1.5.2 The Role of Epigenetics in Immune Diseases -- 1.5.3 Role of Epigenetics in Endocrine Diseases -- 1.5.4 The Role of Epigenetics in Respiratory System Diseases 1.5.5 The Role of Epigenetics in Dermatologic Disorders -- 1.5.6 Role of Epigenetics in Cardiovascular Diseases -- 1.5.7 The Role of Epigenetics in Gastrointestinal Tract Diseases -- 1.6 Discussion -- 1.7 Conclusion -- References -- 2 The Development of Epigenetics in the Study of Disease Pathogenesis -- 2.1 The History and Discovery of the Basic Mechanics of Epigenetics -- 2.1.1 Experimental Observations: Setting the Stage for the Discovery of Epigenetic Mechanisms -- 2.1.2 Getting to the Substance of the Matter: Discoveries of Physical Mechanisms of Epigenetic Control 2.1.3 A New Epigenetic Role for RNA -- 2.2 Epigenetics Moves Mainstream and Meets the Clinic -- 2.2.1 The Epigenetics of Aging -- 2.2.2 The Concept of an Epigenetic Clock -- 2.2.3 Epigenetic Effects of Antiaging Interventions -- 2.3 Epigenetic Modifications as Biomarkers of Disease -- 2.4 Epigenetics in the Modern World: Using Big Data to Understand the Pathogenesis of Complex Diseases in the Present Day -- 2.5 Summary -- References -- 3 Epigenetic Methods and Twin Studies -- 3.1 Introduction -- 3.2 Epigenetic Methods Applied to Rheumatic Diseases 3.3 Epigenetic Twin Studies in Rheumatic Diseases -- 3.4 Conclusions -- References -- Part II Allergic Diseases -- 4 The Role of Genetics, the Environment, and Epigenetics in Atopic Dermatitis -- 4.1 Introduction -- 4.2 Prevalence -- 4.3 Clinical Features -- 4.4 Diagnosis -- 4.5 Pathogenesis -- 4.5.1 Skin Barrier -- 4.5.2 Skin Barrier and AD -- 4.5.3 Immune Imbalance of AD -- 4.5.4 Interaction of Skin Barrier and Immune Function in AD -- 4.5.5 Environmental Factors -- 4.6 GWAS in AD -- 4.7 Epigenetics and AD -- 4.7.1 Epigenetic Studies on the Skin Barrier 4.7.2 Epigenetic Studies on the Immune System -- 4.7.3 miRNAs in AD -- 4.7.4 Epigenetics Studies in AD Patients -- 4.8 Conclusion -- References -- 5 The Epigenetics of Food Allergy -- 5.1 Introduction -- 5.2 Biological Processes in Food Allergy -- 5.3 Genetics -- 5.3.1 Family History -- 5.3.2 Genes Involved in Food Allergy -- 5.4 The Environment -- 5.4.1 The Effect of Early Introduction of Foods -- 5.4.2 The Microbiome -- 5.5 Epigenetic Research in Food Allergies -- 5.6 Conclusions -- References -- 6 Epigenetics and the Environment in Airway Disease: Asthma and Allergic Rhinitis
• Publisher Details: Singapore : Springer
• Publication Date: 2020
• Extent: 1 online resource (408 p.)
• Subjects: 572.8/65; Epigenetics; Immunogenetics; Electronic books; Electronic books
• Languages: English
• ISBNs: 9789811534492; 9811534497
• Related ISBNs: 9789811534485; 9811534489
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.