Functional Polymers by Post-Polymerization Modification : Concepts, Guidelines and Applications.: Concepts, Guidelines and Applications. (2013)

• Record Type: Book
• Other Names: Theato, Patrick; Klok, Harm-Anton
• Contents: Functional Polymers by Post-Polymerization Modification -- Contents -- List of Abbreviations -- List of Contributors -- 1 History of Post-polymerization Modification -- 1.1 Introduction -- 1.2 Post-polymerization Modification via Thiol-ene Addition -- 1.3 Post-polymerization Modification of Epoxides, Anhydrides, Oxazolines, and Isocyanates -- 1.4 Post-polymerization Modification of Active Esters -- 1.5 Post-polymerization Modification via Thiol-Disulfide Exchange -- 1.6 Post-polymerization Modification via Diels-Alder Reactions -- 1.7 Post-polymerization Modification via Michael-Type Addition -- 1.8 Post-polymerization Modification via Azide Alkyne Cycloaddition Reactions -- 1.9 Post-polymerization Modification of Ketones and Aldehydes -- 1.10 Post-polymerization Modifications via Other Highly Efficient Reactions -- 1.11 Concluding Remarks -- References -- 2 Post-polymerization Modifications via Active Esters -- 2.1 Introduction -- 2.2 Active Esters in the Side Group -- 2.2.1 Homopolymers -- 2.2.1.1 General -- 2.2.1.2 Stimuli-Responsive Polymers -- 2.2.1.3 Biologically Active Polymers -- 2.2.1.4 Thin Films -- 2.2.1.5 Polymeric Ligands for Nanoparticles -- 2.2.1.6 Miscellaneous Uses of Active Ester Polymers -- 2.2.2 Block Copolymers -- 2.2.2.1 General -- 2.2.2.2 Block Copolymers and Inorganic Moieties -- 2.2.2.3 Amphiphilic Block Copolymers -- 2.2.2.4 Stimuli-Responsive Block Copolymers -- 2.3 Star Polymers -- 2.4 Active Esters at the End Groups -- 2.5 Controlled Positioning of Active Ester Moieties -- 2.6 Summary -- References -- 3 Thiol-ene Based Functionalization of Polymers -- 3.1 Introduction -- 3.2 General Considerations and Mechanisms -- 3.2.1 Radical Thiol-ene Addition -- 3.2.2 Nucleophilic Thiol-ene Addition -- 3.3 Functionalization of Polymers -- 3.3.1 Endfunctionalization -- 3.3.1.1 Polymer-ene/Thiol -- 3.3.1.2 Polymer-SH/Olefin. 3.3.2 Polymer-Analog Reactions -- 3.3.2.1 Polyene/Thiol -- 3.3.2.2 Polythiol/Olefin -- 3.3.3 Bioconjugation -- 3.4 Summary -- Acknowledgments -- References -- 4 Thiol-yne Chemistry in Polymer and Materials Science -- 4.1 Introduction -- 4.2 The Thiol-yne Reaction in Small-Molecule Chemistry -- 4.3 The Thiol-yne Reaction in Polymer and Material Synthesis -- 4.3.1 Network Polymers -- 4.3.2 Surface-Initiated Polymerizations and Modifications -- 4.3.3 Polymer Beads -- 4.3.4 Hyperbranched Polymers -- 4.3.5 Dendrimers and Dendritic Polymers -- 4.3.6 Main chain a- and w-Functional (co)Polymers -- 4.3.7 Nonradical Thiol-yne Click Polymerization -- 4.3.8 Summary and Outlook -- References -- 5 Design and Synthesis of Maleimide Group Containing Polymeric Materials via the Diels-Alder/Retro Diels-Alder Strategy -- 5.1 Introduction -- 5.2 Maleimide Functional Group Containing Polymeric Materials -- 5.3 The Diels-Alder/Retro Diels-Alder Cycloaddition-Cycloreversion Reactions -- 5.4 Application of Diels-Alder/Retro Diels-Alder Reaction to Synthesize Maleimide-Containing Polymers -- 5.4.1 Synthesis of Polymers Containing the Maleimide Group at the Chain Termini -- 5.4.2 Polymers Containing Maleimide Groups as Side Chains -- 5.4.3 Synthesis of Maleimide-Containing Hydrogels Obtained Using the Diels-Alder/Retro Diels-Alder Reaction-Based Strategy -- 5.5 Conclusions -- References -- 6 The Synthesis of End-Functional Ring-Opening Metathesis Polymers -- 6.1 Introduction -- 6.2 End-Functionalization Methods in General -- 6.3 Functionalization during Initiation -- 6.4 Functionalization after Propagation -- 6.4.1 Reaction with Carbonyl Groups -- 6.4.2 Reaction with Molecular Oxygen -- 6.4.3 Reaction with Functional Vinyl Ethers -- 6.4.4 Reaction with Functional Vinyl Esters -- 6.4.5 Reaction with Nondeactivating Olefins -- 6.5 Functionalization during Propagation. 6.5.1 Using Chain-Transfer Agents -- 6.5.2 Sacrificial Synthesis -- 6.6 Conclusions and Outlook -- Acknowledgments -- References -- 7 Functional Polymers with Controlled Microstructure Based on Styrene and N-Substituted Maleimides -- 7.1 Introduction -- 7.2 Background on Radical Copolymerization of Styrene and Maleimides -- 7.2.1 Conventional Radical Polymerization -- 7.2.2 Controlled Radical Polymerization -- 7.3 Precise Incorporation of Maleimide Units on Polystyrene Backbone -- 7.3.1 Strategy -- 7.3.2 Maleimides -- 7.3.3 Styrene Derivatives -- 7.4 Tuning a Simple Technique for the Preparation of Sequence-Controlled Polymers to the Elaboration of Functionalized Well-Defined Macromolecules -- 7.4.1 Incorporation of Different Functionalities on the Same Polymer Backbone of a Well-Defined Polymer Possessing a Controlled Microstructure -- 7.4.2 Designing 1D Periodic Molecular Arrays -- 7.4.3 Elaboration of New Materials by Post-polymerization Modification -- 7.4.3.1 Activated Esters as Precursor of Post-polymerization Modification -- 7.4.3.2 Formation of Positionable Covalent Bridges -- 7.5 Summary and Outlook -- References -- 8 Temperature-Triggered Functionalization of Polymers -- 8.1 Introduction -- 8.2 Temperature-Triggered Alteration of Polymer Property -- 8.2.1 Thermolysis of t-Butyl Esters, Carbonates, and Carbamates -- 8.2.2 Thermolysis of Miscellaneous Esters, Carbonates, and Carbamates -- 8.2.3 Thermolysis of Acetals -- 8.3 Temperature-Triggered Generation of Reactive Groups -- 8.3.1 Thermolytic Generation of Anhydride Group in Polymers -- 8.3.2 Thermolytic Generation of Ketenes in Polymers -- 8.3.3 Thermolytic Generation of Transient Reactive Groups -- 8.4 Conclusions -- References -- 9 New Functional Polymers Using Host-Guest Chemistry -- 9.1 Introduction -- 9.2 Polymers with Responsive Three-Dimensional Structures. 9.2.1 Helicity Induction -- 9.2.2 Helix Inversion -- 9.3 Polymer Probes for Specific Chemical Sensing -- 9.3.1 Colorimetric Probes -- 9.3.2 Fluorescent Probes -- 9.4 Responsive Soft Materials -- 9.4.1 Responsive Smart Gels -- 9.4.2 Thermoresponsive Materials with Molecular Recognition Ability -- 9.5 Functional Polyrotaxanes -- References -- 10 Glycopolymers via Post-polymerization Modification Techniques -- 10.1 Introduction -- 10.2 Synthesis and Controlled Polymerization of Glycomonomers -- 10.3 Post-polymerization Modification of Polymer Scaffolds to Synthesize Glycopolymers -- 10.4 Azide-Alkyne Click Reactions -- 10.5 Utilizing Thiol-Based Click Reactions -- 10.6 Thiol-ene Click Reactions -- 10.7 Thiol-yne Click Reactions -- 10.8 Thiol-Halogen Substitution Reactions -- 10.9 Alkyne/Alkene Glycosides: "Backward" Click Reactions -- 10.10 Post-polymerization Glycosylation of Nonvinyl Backbone Polymers -- 10.11 Conclusions and Outlook -- Acknowledgments -- References -- 11 Design of Polyvalent Polymer Therapeutics -- 11.1 Introduction -- 11.2 Polyvalent Polymer Therapeutics -- 11.2.1 Polymer Micelles -- 11.2.2 Controlled-Molecular-Weight Linear Polymers -- 11.2.3 Controlled Ligand Spacing -- 11.2.4 Matching Valency to the Target -- 11.2.5 Biocompatible Polymer Scaffolds -- 11.2.6 Bioengineered Polymer Scaffolds -- 11.3 Conclusions -- References -- 12 Posttranslational Modification of Proteins Incorporating Nonnatural Amino Acids -- 12.1 Posttranslational Modification of Existing Amino Acids within Protein Chain -- 12.1.1 Phosphorylation -- 12.1.2 Acetylation -- 12.1.3 Methylation -- 12.1.4 Glycosylation -- 12.1.5 Hydroxylation -- 12.1.6 Sulfation -- 12.2 Exploiting Biosynthetic Machinery: Cotranslational Approach -- 12.2.1 Site-Specific Incorporation (SSI) -- 12.2.1.1 In vitro SSI -- 12.2.1.2 In vivo SSI -- 12.2.1.3 Applications. 12.2.2 Residue-Specific Incorporation (RSI) -- 12.2.2.1 Endogenous AARS -- 12.2.2.2 Overexpression of Endogenous AARS -- 12.2.2.3 Shrinking the AARS Editing Pocket -- 12.2.2.4 Enlarging the AARS Binding Pocket -- 12.2.2.5 Applications -- 12.3 Intein-Inspired Ligation Approach -- 12.3.1 Native Chemical Ligation (NCL) -- 12.3.1.1 Sulfur-Based N-Terminal Residue -- 12.3.1.2 Selenocysteine-Based N-Terminal Residue -- 12.3.2 Expressed Protein Ligation (EPL) -- 12.4 Combined Approach -- 12.4.1 RSI and EPL -- 12.4.2 SSI and Intein-Mediated Ligation -- 12.5 Protein and Polymer Conjugates -- 12.5.1 PEGlyation of Proteins via NAA -- 12.6 Modulating the Physicochemical Properties of Protein Polymers via NAA Incorporation -- 12.7 Future in Combined Technologies to Fabricate Tailored Protein-Polymer Conjugates as New Materials -- 12.8 Conclusion and Future Perspectives -- Acknowledgments -- References -- 13 Functionalization of Porous Polymers from High-Internal-Phase Emulsions and Their Applications -- 13.1 Introduction -- 13.1.1 Preparation Method of polyHIPEs -- 13.2 Functionalization of polyHIPEs -- 13.2.1 Functionalization of polyHIPEs Based on Copolymerization with Functional Comonomers -- 13.2.2 Functionalization of polyHIPEs by Post-polymerization Modification -- 13.2.3 Functionalization of polyHIPEs Based on Grafting Modification of Porous Materials -- 13.2.3.1 ATRP to Functionalize polyHIPEs -- 13.2.4 Click Chemistry for Functionalization of polyHIPEs -- 13.2.5 Thiol-ene-based polyHIPEs -- 13.2.6 Dicyclopentadiene polyHIPEs -- 13.3 Applications -- 13.3.1 Tissue Engineering -- 13.3.2 Support Materials -- 13.4 Conclusions -- References -- 14 Post-polymerization Modification of Polymer Brushes -- 14.1 Introduction -- 14.2 Synthesis and Strategies for Functional Polymer Brushes -- 14.2.1 Preparation of Active Ester Polymer Brushes by SI-ATRP.
• Publisher Details: Somerset : Wiley
• Publication Date: 2013
• Copyright Date: 2012
• Extent: 1 online resource (475 pages)
• Subjects: 668.92; Polymerization; Polymers -- Electric properties; Polymers -- Industrial applications; Polymerization; Polymers -- Electric properties; Polymers -- Industrial applications
• Languages: English
• ISBNs: 9783527655441; 3527655441; 9783527331154; 3527331158
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.