Successful drug discovery. (2015)

• Record Type: Book
• Further Information: Note: Edited by János Fischer and David P. Rotella.
• Editors: Fischer, János; Rotella, David P
• Contents: Part I: General Aspects. Serendipitous Target-Based Drug Discoveries / János Fischer, David P Rotella -- Drug Discoveries and Molecular Mechanism of Action / David C Swinney -- Part II: Drug Class. Insulin Analogs -- Improving the Therapy of Diabetes / John M Beals -- Part III: Case Histories. The Discovery of Stendra (Avanafil) for the Treatment of Erectile Dysfunction / Koichiro Yamada, Toshiaki Sakamoto, Kenji Omori, Kohei Kikkawa -- Dapagliflozin, A Selective SGLT2 Inhibitor for Treatment of Diabetes / William N Washburn -- Elvitegravir, A New HIV-1 Integrase Inhibitor for Antiretroviral Therapy / Hisashi Shinkai -- Discovery of Linagliptin for the Treatment of Type 2 Diabetes Mellitus / Matthias Eckhardt, Thomas Klein, Herbert Nar, Sandra Thiemann -- The Discovery of Alimta (Pemetrexed) / Edward C Taylor -- Perampanel: A Novel, Noncompetitive AMPA Receptor Antagonist for the Treatment of Epilepsy / Shigeki Hibi -- Discovery and Development of Telaprevir (Incivek): A Protease Inhibitor to Treat Hepatitis C Infection / Bhisetti G Rao, Mark Murcko, Mark J Tebbe, Ann D Kwong -- Antibody-Drug Conjugates: Design and Development of Trastuzumab Emtansine (T-DM1) / Sandhya Girish, Gail D Lewis Phillips, Fredric S Jacobson, Jagath R Junutula, Ellie Guardino.
• Publisher Details: Weinheim, Germany : Wiley-VCH
• Publication Date: 2015
• Extent: 1 online resource
• Subjects: 615.1/9; Drugs -- Design; Pharmaceutical chemistry; Designer Drugs; Pharmaceutical Preparations -- chemical synthesis; Drug Design; Models, Molecular; MEDICAL -- Pharmacology; Drugs -- Design; Pharmaceutical chemistry; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783527678433; 3527678433; 1322949557; 9781322949550; 9783527678457
• Related ISBNs: 352767845X
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (John Wiley, viewed February 23, 2015).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.