Trajectories of genetics. (2020)

• Record Type: Book
• Further Information: Note: Bernard Dujon, Georges Pelletier.
• Authors: Dujon, Bernard; Pelletier, Georges
• Contents: Intro -- Table of Contents -- Introduction -- 1 Following Ariadne's Thread from Genetics to DNA -- 1.1. The birth of genetics -- 1.2. The foundations of a new science -- 1.3. Gene, locus and genetic maps -- 1.4. Mutagenesis, first ideas on the material nature of the gene -- 1.5. First ideas on gene products -- 1.6. The order of things and the elements of disorder -- 1.7. Dissecting the invisible: allelism, cistron and the locus again -- 1.8. The DNA trail -- 1.9. Important ideas to remember -- 1.10. References -- 2 The Molecular Nature of Genes and Their Products 2.1. DNA and its replication -- 2.2. Permanence and alteration of DNA, mutations -- 2.3. Protein synthesis and the central dogma of molecular biology -- 2.4. The genetic code: how to read the genetic message -- 2.5. First paradigm of gene expression: the bacterial lactose operon -- 2.6. Reverse transcription and retrogenes -- 2.7. Exons, introns and splicing: the first complexity of RNA life -- 2.8. Sequence editing: the second complexity of RNA life -- 2.9. RNA interference and epigenetics -- 2.10. Important ideas to remember -- 2.11. References -- 3 Chromosomes and Reproduction 3.1. The "true" chromosomes -- 3.2. Sexual reproduction and alternating generations -- 3.3. Meiosis -- 3.4. Genetic determinism of sex -- 3.5. Clonal reproduction and its derivatives -- 3.6. The genetics of organelles -- 3.7. Important ideas to remember -- 3.8. References -- 4 From Genetic Engineering to Genomics -- 4.1. Restriction of DNA -- 4.2. Recombinant DNA and the birth of genetic engineering -- 4.3. Sequencing of biological macromolecules -- 4.4. The beginnings of genomics: the very first genome sequences -- 4.5. The trigger -- 4.6. The impact of the first real genomes 4.7. The human genome -- 4.8. New methods of genome sequencing and the current state of genomics -- 4.9. Important ideas to remember -- 4.10. References -- 5 Uniqueness and Polymorphism of Genomes -- 5.1. The immensity of nucleic acid sequences -- 5.2. Components of genomes and their replication -- 5.3. A little perspective on the content of genomes -- 5.4. Traces of the past and driving forces for the future -- 5.5. Genes in genomes -- 5.6. Genes and genetic determinism -- 5.7. Natural populations: pan-, core-genomes and SNP -- 5.8. Population genomics -- 5.9. The genetics of genomes 5.10. Important ideas to remember -- 5.11. References -- 6 Natural Dynamics and Directed Modifications of Genomes -- 6.1. The dynamics of genomes -- 6.2. Hereditary acquisitions -- 6.3. Directed manipulations of genomes: principles and tools -- 6.4. Directed manipulations of genomes: applications -- 6.5. Important ideas to remember -- 6.6. References -- 7 Of Genes and Humans -- 7.1. Ancient DNA and human history -- 7.2. Traces of the past in today's human genome -- 7.3. Traces of past climates in the trees of our forests -- 7.4. The domestication of cultivated plants
• Publisher Details: London Hoboken, NJ : ISTE Ltd John Wiley & Sons, Inc
• Publication Date: 2020
• Extent: 1 online resource (223 pages), illustrations
• Subjects: 576.5; Genetics; Electronic books
• Languages: English
• ISBNs: 9781119720409; 1119720400; 1119720397; 9781119720393
• Related ISBNs: 178630533X; 9781786305336
• Notes: Note: Includes bibliographical references and index.; Note: Description based on online resource; title from digital title page (viewed on May 14, 2020).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.