Nutrigenomics : how science works /: how science works. (2020)

• Record Type: Book
• Further Information: Note: Carsten Carlberg, Stine Marie Ulven, Ferdinand Molnár.
• Other Names: Carlberg, Carsten; Ulven, Stine Marie; Molnár, Ferdinand
• Contents: Intro -- Preface -- Acknowledgments -- Contents -- Abbreviations -- Chapter 1: Nutrition and Common Diseases -- 1.1 Evolution of Human Nutrition -- 1.2 Principles of Metabolism -- 1.3 Dietary Molecules -- 1.4 Nutrition and Metabolic Diseases -- 1.5 Nutrition and Cancer -- 1.6 Impact of Physical Activity -- Additional Readings -- Chapter 2: Human Genomic Variation -- 2.1 Migration and Evolutionary Challenges of Homo sapiens -- 2.2 Diversity of Human Populations -- 2.3 Genetic Variants of the Human Genome -- 2.4 Haplotype Blocks and GWAS -- 2.5 The 1000 Genomes Project -- Additional Readings Chapter 3: Sensing Nutrition -- 3.1 Nutrient-Sensing Mechanisms -- 3.2 Nuclear Receptors as Nutrient Sensors -- 3.3 Functions and Actions of PPARs -- 3.4 Integration of Lipid Metabolism by LXRs and FXR -- 3.5 Coordination of the Immune Response by VDR -- 3.6 Circadian Control of Metabolic Processes -- Additional Readings -- Chapter 4: Interference of the Human Genome with Nutrients -- 4.1 Human Genetic Adaptions -- 4.2 Genetic Adaption to Dietary Changes -- 4.3 Regulatory SNPs and Quantitative Traits -- 4.4 Definition of Nutrigenomics -- 4.5 Personal Omics Profiles -- Additional Readings Chapter 5: Nutritional Epigenetics -- 5.1 Epigenetic Mechanisms -- 5.2 Intermediary Metabolism and Epigenetic Signaling -- 5.3 Nutrition-Triggered Transgenerational Epigenetic Inheritance -- 5.4 Population Epigenetics -- Additional Readings -- Chapter 6: Nutritional Signaling and Aging -- 6.1 Aging and Conserved Nutrient-Sensing Pathways -- 6.2 Neuroendocrine Regulation of Aging -- 6.3 Principles of Insulin Signaling -- 6.4 Central Role of FOXO Transcription Factors -- 6.5 Calorie Restriction from Yeast to Mammals -- 6.6 Cellular Energy Status Sensing by Sirtuins and AMPK -- Additional Readings Chapter 7: Chronic Inflammation and Metabolic Stress -- 7.1 The Central Role of Monocytes and Macrophages -- 7.2 Acute and Chronic Inflammation -- 7.3 Reverse Cholesterol Transport and Inflammation -- 7.4 Sensing Metabolic Stress via the ER -- Additional Readings -- Chapter 8: Obesity -- 8.1 Definition of Obesity -- 8.2 Adipogenesis -- 8.3 Inflammation in Adipose Tissue -- 8.4 Energy Homeostasis and Hormonal Regulation of Food Uptake -- 8.5 Genetics of Obesity -- Additional Readings -- Chapter 9: Insulin Resistance and Diabetes -- 9.1 Glucose Homeostasis
• Publisher Details: Cham : Springer
• Publication Date: 2020
• Extent: 1 online resource (195 pages)
• Subjects: 612.3; Nutrition -- Genetic aspects; Nutrition -- Genetic aspects; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783030369484
• Related ISBNs: 303036948X; 9783030369477; 3030369471
• Notes: Note: Includes bibliographical references.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.