Heat shock protein 90 in human diseases and disorders. (2019)

• Record Type: Book
• Further Information: Note: Alexzander A.A. Asea, Punit Kaur, editors.
• Other Names: Asea, Alexzander A. A; Kaur, Punit
• Contents: SECTION I: ONCOGENIC ASPECTS OF HSP90 -- Chapter 1. Regulatory Roles of HSP90-rich Extracellular Vesicles -- Chapter 2. HSP90-Based Heterocomplex as Essential Regulator for Cancer Disease -- Chapter 3. Therapeutic Potential of Heat Shock Protein 90 Inhibitors in Colorectal Cancer -- Chapter 4. Hsp90 in the Migration of Primordial Germ Cells: A Model to Study Long-Distance Cell Migration and Perhaps Cancer? -- Chapter 5. Role of Heat Shock Protein 90 in Mammary Tumorigenesis -- Chapter 6. Role of HSP90 Inhibitors in the Treatment of Cancer -- Chapter 7. p53-HSP90 Axis in Human Cancer -- Chapter 8. HSP90 and its Inhibitors for Cancer Therapy: Use of Nano-delivery System to Improve its Clinical Application -- Chapter 9. Hsp90 is a Pivotal Player in Retinal Disease and Cancer -- Chapter 10. Targeting Hsp-90 Related Disease Entities for Therapeutic Development -- Chapter 11. HSP90: A Key Player in Metal-Induced Carcinogenesis? -- Section II: Biomolecular Aspects of HSP90 -- Chapter 12. Hsp90 and its Role in Heme-Maturation of Client Proteins: Implications for Human Diseases -- Chapter 13. Moonlighting Functions of Heat Shock Protein 90 -- Chapter 14. Hsp90 as a Member of Dicarboxylate Clamp TPR Protein Interaction Network: Implication in Human Diseases and Prospect as a Drug Target -- Chapter 15. 'Complex World' of Hsp90 Co-chaperone R2TP -- Chapter 16. Functions of SGT1, a Co-chaperone -- Chapter 17. Sti1/Hop Plays a Pivotal Role in Hsp90 Regulation beyond Bridging Hsp70 -- Section III: HSP90 in Natural Products Development.-Chapter 18. Hsp90: A Target for Susceptibilities and Substitutions in Biotechnological and Medicinal Application -- Chapter 19. Screening Technique for Heat Shock Protein 90 Inhibitors from Natural Products -- Chapter 20. Therapeutic Effects and Related Molecular Mechanisms of Celastrol, a Triterpenoid Natural Compound and Novel HSP90 Inhibitor Extracted from Plants of the Celastraceae Family -- Section IV: Clinical Aspects of HSP90 -- Chapter 21. Hsp90 Chaperone in Disease -- Chapter 22. Theranostic Implications of Heat Shock Proteins in Idiopathic Pulmonary Fibrosis -- Chapter 23. Heat Shock Protein 90 and Reproduction in Female Animals: Ovary, Oocyte and Early Embryo -- Chapter 24. Heat Shock Protein 90 in Severe Trauma -- Chapter 25. HSP90 -- Is there an Unknown Role in Pain Neurobiology -- Chapter 26. Heat Shock Protein 90 in Kidney Stone Disease -- Chapter 27. HSP90 et al. -- Chaperome and Proteostasis Deregulation in Human Disease.
• Publisher Details: Cham : Springer
• Publication Date: 2019
• Extent: 1 online resource (599 pages)
• Subjects: 572/.6; Heat shock proteins; Heat shock proteins; Electronic books
• Languages: English
• ISBNs: 9783030231583; 3030231585
• Related ISBNs: 9783030231576; 3030231577
• Notes: Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.