Polycystic kidney disease. (2019)

• Record Type: Book
• Further Information: Note: Editors, Jinghua Hu, Ph.D., Yong Yu, Ph.D.
• Authors: Hu, Jinghua
• Editors: Hu, Jinghua; (Biological sciences), Yu, Yong
• Contents: 1. Biochemical Analysis of the Polycystin-1 Complexity Generated by Proteolytic Cleavage at the G Protein-Coupled Receptor Proteolysis Site. 2. Structural Determination of the Polycystin-2 Channel by Electron Cryo-Microscopy. 3. Recording Ion Channels in Cilia Membranes. 4. Electrophysiological Recording of a Gain-of-Function Polycystin-2 Channel with a Two-Electrode Voltage Clamp. 5. Functional Studies of PKD2 and PKD2L1 through Opening the Hydrophobic Activation Gate. 6. Analyzing the GPCR Function of Polycystin-1. 7. Methods to Study the Vasculature in ADPKD. 8. Energy Metabolism, Metabolic Sensors, and Nutritional Interventions in Polycystic Kidney Disease. 9. “Kidney in a Dish” Organoids for PKD. 10. Rodent Autosomal Dominant Polycystic Kidney Disease Models. 11. Using C. elegans as a Model in PKD. 12. Approaches to Studying Polycystic Kidney Disease in Zebrafish. 13. Investigation of DNA Methylation in Autosomal Dominant Polycystic Kidney Disease. 14. Molecular Diagnosis of Autosomal Dominant Polycystic Kidney Disease.
• Edition: 1st
• Publisher Details: Boca Raton : CRC Press
• Publication Date: 2019
• Extent: 1 online resource, illustrations (black and white, and colour)
• Subjects: 616.61042; Polycystic kidney disease; Polycystic kidney disease -- Genetic aspects
• Languages: English
• ISBNs: 9780429888946; 9780429888953; 9780429888939; 9780429468834
• Related ISBNs: 9781138603899
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.