Snake and spider toxins : methods and protocols /: methods and protocols. (2020)

• Record Type: Book
• Further Information: Note: Edited by Avi Priel.
• Editors: Priel, Avi
• Contents: Preface… Table of Contents… Contributing Authors… Part I Overview 1. Snake- and Spider-Venom-Derived Toxins as Lead Compounds for Drug Development Philip Lazarovici 2. Analytics for Bioactivity Profiling of Complex Mixtures with a Focus on Venoms Marija Mladic, Wilfried M.A. Niessen, Govert W. Somsen, and Jeroen Kool Part II Toxins Purification and Production 3. Venom Collection from Spiders and Snakes: Voluntary and Involuntary Extractions ('Milking') and Venom Gland Extractions William K. Hayes, Gerad A. Fox, and David R. Nelsen 4. Production and Purification of Recombinant Toxins Matan Geron Part III Toxins Characterization 5. RNA-Sequencing of Snake Venom Glands Khin Than Yee, Olga Vasieva, and Ponlapat Rojnuckarin 6. Exploring Toxin Evolution: Venom Protein Transcript Sequencing and Transcriptome-Guided High-Throughput Proteomics Cassandra M. Modahl, Jordi Durban, and Stephen P. Mackessy 7. Three-Dimensional Structure Determination of Peptides using Solution Nuclear Magnetic Resonance Spectroscopy Christina I. Schroeder and K. Johan Rosengren 8. Determining the Structures of the Snake and Spider Toxins by X-Rays Anwar Ullah, Rehana Masood, Zafar Hayat, and Ahmed Hafeez 9. MALDI-TOF Mass Spectrometric Profiling of Spider Venoms Ondrej Šedo, Stano Pekár, and Zbyněk Zdráhal Part IV Characterization of Toxins Function 10. Methods for Evaluation of a Snake Venom Derived Disintegrin in Animal Models of Human Cancer Stephen D. Swenson, Catalina Silva-Hirschberg, and Francis S. Markland 11. Cell-Based Adhesion Assays for Isolation of Snake Venom's Integrin Antagonists Philip Lazarovici, Cezary Marcinkiewicz, and Peter I. Lelkes 12. Using C. elegans to Study the Effects of Toxins in Sensory Ion Channels In Vivo Valeria Vásquez 13. Measurements of Cell Death Induced by Snake and Spider's Venoms and Derived Toxins Yossi Maatuf, Avi Priel and Philip Lazarovici 14. Using Toxins in Brain Slice Recordings Alexey Bingor and Rami Yaka 15. High-Throughput Calcium Imaging Screen of Toxins' Function in Dissociated Sensory Neurons Yossi Maatuf and Avi Priel 16. Synthesizing and Expressing Native Ion Channels Shana L. Geffeney and Charles T. Hanifin.
• Publisher Details: New York, NY : Humana Press
• Publication Date: 2020
• Extent: 1 online resource (x, 293 pages), illustrations (some color)
• Subjects: 571.9/5; Poisonous snakes -- Venom -- Laboratory manuals; Poisonous spiders -- Venom -- Laboratory manuals; Electronic books
• Languages: English
• ISBNs: 9781493998456; 1493998455
• Related ISBNs: 9781493998449
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed October 8, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.