Cutaneous photoaging. (2019)

• Record Type: Book
• Further Information: Note: Editors: Rachel E.B. Watson, Christopher E.M. Griffiths.
• Editors: Watson, Rachel E. B; Griffiths, C (Christopher)
• Contents: Cover; Comprehensive Series in Photochemical and Photobiological Science; Preface; Contents; Chapter 1 -- Photoaging in Caucasians; 1.1. The Scope of the Photoaging Problem; 1.2. Introduction; 1.3. Intrinsic Aging; 1.3.1. Histological Changes of Intrinsic Aging; 1.4. Extrinsic Aging; 1.5. Histological Changes of Extrinsic Aging; 1.6. Elastic Fibres; 1.7. Fibrillin-rich Microfibrils; 1.8. Collagens; 1.8.1. Fibrillar Collagens I and III; 1.8.2. Collagen VII and Laminin-332; 1.9. CD44 and Hyaluronidase; 1.10. Vascular Factors; 1.11. Morphometric Measurements; 1.12. Photonumeric Scales 1.13. ConclusionsReferences; Chapter 2 -- Photodamage in Skin of Color; 2.1. Introduction; 2.1.1 .Defining Skin Types; 2.1.2. Structural Differences in Skin of Color; 2.1.2.1. Epidermis.The outermost layer of the skin plays a significant role as a barrier from environmental insults. The epidermi...; 2.1.2.1.1. Keratinocytes.Keratinocytes are key epidermal cells. They play an integral role in maintaining the structural integrit...; 2.1.2.1.2. Melanocytes.Melanocytes are derived from the neural crest, and migrate to the epidermis during embryogenesis. Melanocy... 2.1.2.1.3. Melanin.There is a strong correlation between skin pigmentation and melanin content in surface keratinocytes.17 Differ...2.1.2.2. Dermis.While pigmentation is certainly the most striking variance between ethnicities, morphological differences in the ...; 2.2. Skin Aging: Intrinsic and Extrinsic Pathways; 2.2.1. Photobiological Responses in Skin of Color; 2.2.1.1. Ultraviolet Radiation Exposure.UVR accounts for approximately 7% of solar radiation. It is divided into UVA (320-400 nm)... 2.2.1.1.1. Erythema.UVB is 1000 times more erythemogenic than UVA. A well- recognized characteristic of ethnic skin is the decrea...2.2.1.1.2. Pigmentation.UVR exposure stimulates pigmentation in all but the fairest skin types (FSPC I). UV- related tanning is c...; 2.2.1.1.3. Photoaging and Photocarcinogenesis.UVR causes ROS production. In addition to this, UV irradiation depletes endogenous ...; 2.2.1.2. Visible Light Exposure.The visible light (VL) spectrum ranges from 400 to 760 nm. VL comprises up to 44% of solar radiat... 2.2.1.2.1. Erythema.The erythemogenic effect of visible light on skin has been attributed to a thermal component. It is hypothesi...2.2.1.2.2. Pigmentation.Similar to UVR, VL exposure is associated with the induction of pigmentation, both in vivo and ex vivo. I...; 2.2.1.2.3. Photoaging and Photocarcinogenesis.Liebel et al. reported a dose- dependent increase of ROS, inflammatory cytokines, a...; 2.2.1.3. Infrared Exposure.Infrared (IR) accounts for approximately 40% of solar radiation reaching the earth's surface. IR is di...
• Publisher Details: Cambridge : Royal Society of Chemistry
• Publication Date: 2019
• Extent: 1 online resource (362 pages)
• Subjects: 616.5/15; Photosensitivity disorders; Skin -- Aging; Electronic books; Electronic books
• Languages: English
• ISBNs: 9781788015981; 1788015983; 9781788018609; 1788018605
• Related ISBNs: 9781788011266; 1788011260
• Notes: Note: Title details screen.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.