Molecular structures and structural dynamics of prion proteins and prions : mechanism underlying the resistance to prion diseases /: mechanism underlying the resistance to prion diseases. ([2015])

• Record Type: Book
• Further Information: Note: Jiapu Zhang.
• Authors: Zhang, Jiapu
• Contents: Basic Knowledge -- The Homology Structure and Dynamics -- The NMR Structure and Dynamics of the Wild-type and Mutants -- Compared with the NMR Structure and Dynamics of Humans and Mice -- Compared with the NMR Structure and Dynamics of Dogs and Horses -- Compared with a Homology Structure and Dynamics of Buffaloes -- Compared with NMR Structure and Dynamics of Elks -- Compared with the X-ray Structure and Dynamics of Rabbits -- Surface Electrostatic Charge Distributions -- The Hydrophobic Region PrP(109-136) -- The Hybrid Method of Steepest Descent -- Conjugate Gradient with Simulated Annealing -- Hybrid Method of Discrete Gradient with Simulated Annealing or Genetic Algorithm -- A Novel Canonical Dual Global Optimization Computational Approach -- The Hybrid Method of Evolutionary Computations with Simulated Annealing -- Simulated Annealing Refined Replica Exchange Global Search Algorithm -- LBFGS Quasi-Newtonian Methods for MM Prion AGAAAAGA Amyloid Fibrils -- Particle Swarm Global Optimization Search Algorithm -- A Summary of the Research Works on AGAAAAGA.
• Publisher Details: Dordrecht : Springer
• Publication Date: 2015
• Extent: 1 online resource
• Subjects: 616.8; Prions; Prion diseases; Natural immunity; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; MEDICAL -- Neurology; Natural immunity; Prion diseases; Prions; Biochemistry; Chemistry; Physical Sciences & Mathematics; Prion Diseases; Prions; Immunity, Innate; Electronic books
• Languages: English
• ISBNs: 9789401773188; 9401773181; 9401773173; 9789401773171
• Related ISBNs: 9789401773171
• Notes: Note: Includes bibliographical references and index.; Note: Vendor-supplied metadata.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.