Therapeutic enzymes : functions and clinical implications /: functions and clinical implications. (2019)

• Record Type: Book
• Further Information: Note: Nikolaos Labrou, editor.
• Other Names: Labrou, Nikolaos E
• Contents: Chapter 1. Introduction to therapeutic enzymes -- Chapter 2. Upstream processing technologies -- Chapter 3. Downstream processing technologies -- Chapter 4. Enzyme Manufacturing Process and Quality Control Evaluations -- Chapter 5. Regulatory guidance in the production of therapeutic enzymes -- Chapter 6. Biophysical methods for the characterization of Enzyme Therapeutics Bertrand Raynal Patrick England -- Chapter 7. Clinical Development of a therapeutic enzyme -- Chapter 8. Chemical modifications of therapeutic proteins -- Chapter 9. Formulation of therapeutic enzymes -- Chapter 10. Engineering of therapeutic enzymes for improving activity -- Chapter 11. Engineering of therapeutic enzymes for improving stability -- Chapter 12. Design and engineering of deimmunized therapeutic enzymes -- Chapter 13. Nanoparticles for delivery of therapeutic enzymes -- Chapter 14. Targeted delivery of therapeutic enzymes -- Chapter 15. Oral and inhalable enzyme therapies -- Chapter 16. Regulatory issues -- Chapter 17. Enzyme replacement therapies -- Chapter 18. Pharmacodynamics and pharmacokinetics issues of enzyme replacement therapy -- Chapter 19. Enzyme therapy for lysosomal storage disorders -- Chapter 20. Enzyme therapy for myocardial infarction -- Chapter 21. Enzyme therapy for chronic gout -- Chapter 22. Enzyme therapy for tumor lysis syndrome -- Chapter 23. Enzyme therapy for collagen-based disorders -- Chapter 24. Enzyme therapy for severe combined immunodeficiency disease -- Chapter 25. Enzyme therapy for detoxification of methotrexate -- Chapter 26. Enzyme therapy vitreomacular adhesion -- Chapter 27. L-Asparaginase as anticancer agent -- Chapter 28. Pancreatic enzyme replacement therapy -- Chapter 29. Enzymes in metabolic anticancer therapy -- Chapter 30. L-Arginase for L-Arg depletion therapy in cancer -- Chapter 31. Methionine L-lyase for L-Met depletion therapy in cancer -- Chapter 32. Enzyme therapy for celiac sprue -- Chapter 33. Acid ceramidase -- Chapter 34. Lysoso mal acid lipase -- Chapter 35. Alkaline phosphatase and hypophosphatasia -- Chapter 36. Enzybiotics: Antibiotic enzymes as drugs and therapeutics -- Chapter 37. Anti-inflammatory enzymes -- Chapter 38. Phenylalanine ammonia lyase for the treatment of phenylketonuria -- Chapter 39. Clinical applications of Hyaluronidase -- Chapter 40. Superoxide dismutase and oxidative stress modulation -- Chapter 41. Organophosphate hydrolases as catalytic bioscavengers -- Chapter 42. Novel therapeutic proteases -- Chapter 43. Genome-editing enzymes -- Chapter 44. Gene therapy for enzyme deficiency: current status and future prospects.
• Publisher Details: Singapore : Springer
• Publication Date: 2019
• Extent: 1 online resource (388 pages)
• Subjects: 615/.35; Enzymes -- Therapeutic use; Enzymes -- Therapeutic use; Electronic books
• Languages: English
• ISBNs: 9789811377099; 9789811377082; 9811377081
• Related ISBNs: 981137709X
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed September 20, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.