Bayesian applications in pharmaceutical development. (2019)

• Record Type: Book
• Further Information: Note: Edited by Mani Lakshminarayanan, Fanni Natanegara.
• Editors: Lakshminarayanan, Mani; Natanegara, Fanni
• Contents: Preface 1. Introduction 2. Incorporation of Historical Control Data in Analysis of Clinical Trials 3. Practical considerations for building priors for confirmatory studies 4. The Practice of Prior Elicitation 5. Bayesian examples in preclinical in-vivo research 6. Planning a model-based Bayesian dose response study 7. Novel Designs for Early Phase Drug Combination Trials 8. Executing and Reporting Clinical Trial Simulations: Practical Recommendations for Best Practices 9. Reporting of Bayesian Analyses in Clinical Research: Some Recommendations 10. Handling missing data in clinical trials with Bayesian and Frequentist Approaches 11. Bayesian Applications in Pharmaceutical Development 12. Simulation for Bayesian Adaptive Designs – Step-by-Step Guide for Developing the Necessary R Code 13. Power Priors for Sample Size Determination in the Process Validation Life-Cycle 14. Bayesian Approaches in the Regulation of Medical Products 15. Computational tools 16. Software for Bayesian Computation - An Overview of Some Currently Available Tools 17. Considerations and Bayesian Applications in Pharmaceutical Development for Rare Diseases 18. Extrapolation Process in Pediatric Drug Development and Corresponding Bayesian Implementation for Validating Clinical Efficacy 19. BM- Appendix: A Brief Guide to Bayesian Model Checking
• Edition: 1st
• Publisher Details: Boca Raton : Chapman & Hall/CRC
• Publication Date: 2019
• Extent: 1 online resource
• Subjects: 615.1901519542; Drug development -- Statistical methods; Bayesian statistical decision theory
• Languages: English
• ISBNs: 9781351584166; 9781351584173; 9781351584159; 9781315099798
• Related ISBNs: 9781138296763
• Notes: Note: Description based on CIP data; resource not viewed.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.