The DNA, RNA, and histone methylomes. ([2019])

• Record Type: Book
• Further Information: Note: Stefan Jurga, Jan Barciszewski, editors.
• Editors: Jurga, Stefan; Barciszewski, Jan
• Contents: Chapter 1. Establishment, Erasure and Synthetic Reprogramming of DNA Methylation in Mammalian Cells.- Chapter 2. Origin and Mechanisms of DNA Methylation Dynamics in Cancers.- Chapter 3. CpG Islands Methylation Alterations in Cancer: Functionally Intriguing Security Locks, Useful Early Tumor Biomarkers.- Chapter 4. Histone and DNA Methylome in Neurodegenerative, Neuropsychiatric and Neurodevelopmental Disorders.- Chapter 5. DNA Methylation in Neuronal Development and Disease.- Chapter 6. Functional Implications of Dynamic DNA Methylation for the Developing, Aging and Diseased Brain.- Chapter 7. The Methylome of Bipolar Disorder: Evidence from Human and Animal Studies.- Chapter 8. DNA Methylation in Multiple Sclerosis.- Chapter 9. Early Life Stress and DNA Methylation.- Chapter 10. Regulation of 5-hydroxymethylcytosine Distribution by the TET Enzymes.- Chapter 11. Epigenetic Alterations: The Relation Between Occupational Exposure and Biological Effects in Humans.- Chapter 12. DNA Methylation: Biological Implications and Modulation of its Aberrant Dysregulation.- Chapter 13. Functions and Dynamics of Methylation in Eukaryotic mRNA.- Chapter 14. The Role of mRNA m6A in Regulation of Gene Expression.- Chapter 15. G9a and G9a-like Histone Methyltransferases and Their Effect on Cell Phenotype, Embryonic Development, and Human Disease.- Chapter 16. Biomolecular Recognition of Methylated Histones.- Chapter 17. The Role of Protein Lysine Methylation in the Regulation of Protein Function - Looking Beyond the Histone Code.- Chapter 18. Secondary Structures of Histone H3 Proteins with Unmethylated and Methylated Lysine-4 and -9 Resiudes; Characterization Using Circular Dichroism Spectroscopy.- Chapter 19. Asymmetric Dimethylation on Arginine (ADMA) of Histones in Development, Differentiation and Disease.- Chapter 20. A Switch for Transcriptional Activation and Repression: Histone Arginine Methylation.- Chapter 21. Aberrant Epigenomic Regulatory Networks in Multiple Myeloma and Strategies for their Targeted Reversal.- Chapter 22. Metabolic Deregulations Affecting Chromatin Architecture: One-carbon Metabolism and Krebs Cycle Impact Histone Methylation.- Chapter 23. Histone Methylome of the Human Parasite Schistosoma Mansoni.
• Publisher Details: Cham : Springer
• Publication Date: 2019
• Copyright Date: 2019
• Extent: 1 online resource, illustrations (some color)
• Subjects: 572.8/645; Methyltransferases; Nucleic acids -- Methylation; Electronic books
• Languages: English
• ISBNs: 9783030147921; 3030147924
• Related ISBNs: 9783030147914
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed September 13, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.