G-quadruplex nucleic acids : methods and protocols /: methods and protocols. (2019)

• Record Type: Book
• Further Information: Note: Edited by Danzhou Yang, Clement Lin.
• Editors: Yang, Danzhou; Lin, Clement
• Contents: Preface…Table of Contents…Contributing Authors… 1. G-Quadruplex DNA and RNADanzhou Yang 2. CD Study of the G-Quadruplex ConformationIva Kejnovská, Daniel Renčiuk, Jan Palacký, and Michaela Vorlíčková 3. Revealing the Energetics of Ligand-Quadruplex Interactions using Isothermal Titration CalorimetryAndrea Funke and Klaus Weisz 4. Biosensor-Surface Plasmon Resonance: Label Free Method for Investigation of Small Molecule-Quadruplex Nucleic Acid InteractionsAnanya Paul, Caterina Musetti, Rupesh Nanjunda, and W. David Wilson 5. Putting a New Spin of G-Quadruplex Structure and Binding by Analytical UltracentrifugationWilliam L. Dean, Robert D. Gray, Lynn DeLeeuw, Robert C. Monsen, and Jonathan B. Chaires 6. Mass Spectroscopic Study of G-QuadruplexHuihui Li 7. G-Quadruplex Stability from DSC MeasurementsSan Hadži, Matjaž Bončina, and Jurij Lah 8. X-Ray Crystallographic Studies of G-Quadruplex StructuresGary N. Parkinson and Gavin W. Collie 9. NMR Studies of G-Quadruplex Structures and G-Quadruplex-Interactive CompoundsClement Lin, Jonathan Dickerhoff, and Danzhou Yang 10. Using Molecular Dynamics Free Energy Simulation to Compute Binding Affinities of DNA G-Quadruplex LigandsNanjie Deng 11. Electrophoretic Mobility Shift Assay and Dimethyl Sulfate Footprinting for Characterization of G-Quadruplexes and G-Quadruplex-Protein ComplexesBuket Onel, Guanhui Wu, Daekyu Sun, Clement Lin, and Danzhou Yang 12. A DNA Polymerase Stop Assay for Characterization of G-Quadruplex Formation and Identification of G-Quadruplex-Interactive Compounds Guanhui Wu and Haiyong Han 13. Chromatin Immunoprecipitation Assay to Analyze the Effect of G-Quadruplex Interactive Agents on the Binding of RNA Polymerase II and Transcription Factors to a Target Promoter Region Daekyu Sun 14. Characterization of Co-Transcriptional Formation of G-Quadruplexes in Double-Stranded DNA Ke-wei Zheng, Jia-yu Zhang, and Zheng Tan 15. Quantitative Analysis of Stall of Replicating DNA Polymerase by G-Quadruplex Formation Shuntaro Takahashi and Naoki Sugimoto 16. Single-Molecule Investigations of G-QuadruplexShankar Mandal, Mohammed Enamul Hoque, and Hanbin Mao 17. Direct Observation of the Formation and Dissociation of Double-Stranded DNA Containing G-Quadruplex/i-motif Sequences in the DNA Origami Frame using High-Speed AFMMasayuki Endo, Xiwen Xing, and Hiroshi Sugiyama 18. G-Quadruplex and Protein Binding by Single-Molecule FRET Microscopy Chun-Ying Lee, Christina McNerney, and Sua Myong 19. High-Throughput Screening of G-Quadruplex Ligands by FRET AssayKaibo Wang, Daniel P. Flaherty, Lan Chen, and Danzhou Yang 20. Targeting G-Quadruplexes with PNA OligomersBruce A. Armitage 21. Primer-Modified G-Quadruplex-Au Nanoparticles for Colorimetric Assay of Human Telomerase Activity and Initial Screening of Telomerase InhibitorsFang Pu, Jinsong Ren, and Xiaogang Qu 22. Heme•G-Quadruplex DNAzymes: Conditions for Maximizing their Peroxidase ActivityNisreen Shumayrikh and Dipankar Sen 23. In Vivo Chemical Probing for G-Quadruplex FormationFedor Kouzine, Damian Wojtowicz, Arito Yamane, Rafael Casellas, Teresa M. Przytycka, and David L. Levens 24. G-Quadruplex Visualization In Cells via Antibody and Fluorescence ProbeMatteo Nadai and Sara N. Richter 25. In Cell NMR Spectroscopy: Investigation of G-Quadruplex Structures inside Living Xenopus laevis OocytesMichaela Krafcikova, Robert Hänsel-Hertsch, Lukas Trantirek, and Silvie Foldynova-Trantirkova 26. 19F NMR Spectroscopy for the Analysis of DNA G-Quadruplex Structures using 19F-labeled NucleobaseTakumi Ishizuka, Hong-Liang Bao, and Yan Xu.
• Publisher Details: New York, NY : Humana Press
• Publication Date: 2019
• Extent: 1 online resource (xiv, 437 pages), illustrations (some color)
• Subjects: 572.8; Quadruplex nucleic acids; Electronic books
• Languages: English
• ISBNs: 9781493996667; 1493996665
• Related ISBNs: 9781493996650
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed September 11, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.