Stem cell transplantation for autoimmune diseases and inflammation. ([2019])

• Record Type: Book
• Further Information: Note: Phuc Van Pham, editor.
• Editors: Pham, Phuc Van
• Contents: Intro; Preface; Contents; Contributors; Part I: Stem Cell Therapy for Autoimmune Diseases; Chapter 1: Current Status of Stem Cell Transplantation for Autoimmune Diseases; 1.1 Introduction; 1.2 Mechanisms of Autoimmune Disease and Stem Cell Therapy Strategy; 1.3 Immune Correction by Hematopoietic Stem Cell Transplantation; 1.3.1 Hematopoietic Stem Cells; 1.3.2 Sources of HSCs for Transplantation; 1.3.3 HSC Transplantations in AD Treatment in Preclinical Trials; 1.3.4 HSC Transplantation for AD Treatment in the Clinic; 1.3.4.1 HSCT for Systemic Sclerosis (SSc) 1.3.4.2 HSCT for Systemic Lupus Erythematosus (SLE)1.3.4.3 HSCT for Rheumatoid Arthritis (RA); 1.3.5 The Mechanisms of HSC Transplantation for AD Treatment; 1.4 Immunomodulation by MSC Transplantation; 1.4.1 Mesenchymal Stem Cells; 1.4.2 MSC Transplantation for ADs in Preclinical Studies; 1.4.3 MSC Transplantation for ADs in the Clinic; 1.4.3.1 MSC Transplantation for SLE; 1.4.3.2 MSC Transplantation for Crohn's Disease; 1.4.3.3 MSC Transplantation for Multiple Sclerosis (MS); 1.5 Conclusion; References; Chapter 2: Mechanisms of Mesenchymal Stem Cells for Autoimmune Disease Treatment 2.1 Introduction2.2 Cellular Mechanism of Autoimmunity; 2.3 Molecular Mechanism of Autoimmunity; 2.4 MSCs in Treating Autoimmunity; 2.5 Mechanism of MSCs in Treating Autoimmune Diseases; 2.6 Mechanism of EVs from MSCs in Treating Autoimmune Diseases; 2.7 Conclusion; References; Chapter 3: Stem Cell Therapy for Multiple Sclerosis: An Exciting Challenge or a Treatment Hope; 3.1 Introduction; 3.1.1 Objectives; 3.1.2 The Importance of Stem Cells; 3.2 Stem Cell Therapy for MS; 3.3 Evidence-Based Experimental Tests of Stem Cell Therapy for MS; 3.4 Epidermal Nerve Stem Cells (EPI-NCSCs) 3.5 Mesenchymal Stem Cells (MSCs)3.6 Neural Stem Cells (NSCs); 3.7 Olfactory Ensheathing Cells (OECs); 3.8 Hematopoietic Stem Cells (HSCs); 3.9 Oligodendrocyte Precursor Cells (OPCs); 3.10 Evidence-Based Clinical Trial of Stem Cell Therapy for MS; 3.11 Hematopoietic Stem Cells (HSCs); 3.12 Mesenchymal Stem Cells (MSCs); 3.13 Adipose Stem Cells (ASCs); 3.14 Nervous Stem Cells (NSCs); 3.15 Conclusion and Future Perspectives; References; Chapter 4: Mesenchymal Stem Cell Transplantation in Rheumatoid Arthritis; 4.1 Introduction; 4.2 Mechanism of Inflammation in Rheumatoid Arthritis and the MSC 4.2.1 Innate Immunity in Rheumatoid Arthritis-Macrophages4.2.2 Innate Immunity in RA-Osteoclasts; 4.2.3 Innate Immunity in RA-NK Cells; 4.2.4 Innate Immunity in RA-Dendritic Cells; 4.2.5 Adaptive Immunity in RA-T Cell Mechanisms; 4.2.6 Adaptive Immunity in RA-B Cell Mechanisms; 4.3 Autologous and Allogeneic Use in RA; 4.3.1 Intravenous vs. Intra-articular Injection; 4.3.2 Priming MSCs; 4.3.3 Clinical Trials; 4.3.3.1 Intravenous Infusion of Umbilical Cord MSCs-Single-Dose Regime; 4.3.3.2 Intravenous and Intra-articular Infusion of Adipose Tissue MSCs-A Split Dose Regime
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2019
• Extent: 1 online resource (169 pages)
• Subjects: 616.978; Autoimmune diseases -- Treatment; Inflammation -- Treatment; Stem cells -- Transplantation; Electronic books
• Languages: English
• ISBNs: 9783030234218; 3030234215
• Notes: Note: Includes bibliographical references.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.