Hepatocellular Carcinoma : Translational Precision Medicine Approaches /: Translational Precision Medicine Approaches. (2019)

• Record Type: Book
• Further Information: Note: Yujin Hoshida, editor.
• Other Names: Hoshida, Yujin
• Contents: Intro; Preface; Acknowledgments; Contents; Contributors; Part I: Clinical Demographics and Management; Chapter 1: Risk Factors of Hepatocellular Carcinoma for Precision Personalized Care; Introduction; Overview of HCC Prevention Strategies; Regular HCC Screening; Clinical Scores to Predict HCC Risk; Molecular Biomarkers to Predict HCC Risk; HCC Detection Modalities and Biomarkers for Regular HCC Screening; HCC Biomarker Development; Individual Risk-Based Tailored HCC Screening; Conclusions; References; Chapter 2: Hepatocellular Carcinoma Surveillance and Staging; HCC Surveillance Benefits of HCC SurveillancePatients with Chronic HBV Infection; Patients with Cirrhosis; Harms of HCC Surveillance; Surveillance Tests; Radiographic Surveillance Tests; Serologic Surveillance Tests; Surveillance Interval; Surveillance Utilization; HCC Surveillance Cost-Effectiveness; Staging; Barcelona Cancer Liver Cancer (BCLC); Hong Kong Liver Cancer (HKLC); Additional HCC Staging Systems; Conclusion; References; Chapter 3: Changing Epidemiology of Hepatocellular Carcinoma and Role of Surveillance; Introduction; HCC Incidence and Mortality Trends; Knowledge Gaps in HCC Surveillance Significance of Mathematical Modeling for Surveillance of HCCCost-Effectiveness of HCC Surveillance by Etiology; Hepatitis C Patients After Viral Cure; Nonalcoholic Fatty Liver Disease; Alcoholic Liver Disease; Heavy Alcohol Consumption with HBV/HCV; Conclusions; References; Part II: Diagnosis and Prognostication; Chapter 4: Radiological Diagnosis and Characterization of HCC; Introduction; Imaging Modalities; Ultrasound and Contrast-Enhanced Ultrasound; Contrast-Enhanced CT; MRI; MRI with ECCM; MRI with Liver-Specific Agents; Positron Emission Tomography-CT and MRI; Imaging Characteristics Diagnostic Imaging FeaturesAncillary Imaging Features; Staging; Quantitative Imaging in HCC; CT and MR Perfusion; Dual Energy CT; Diffusion-Weighted Imaging; Radiomics Quantification; Conclusion; References; Chapter 5: Analysis of Hepatocellular Carcinoma Tissue for Biomarker Discovery; Introduction; Treatment Options; Current Detection Methods; Glycosylation and Biomarkers of Hepatocellular Carcinoma; Broad Tissue Analysis in Hepatocellular Carcinoma; HCC Tissue Proteomics; HCC Glycomics; Future Directions and Conclusions; References Chapter 6: Molecular Subtypes and Genomic Signatures of Hepatocellular Carcinoma for Prognostication and Therapeutic Decision-MakingIntroduction; Clinical Staging of Hepatocellular Carcinoma; Molecular Profiling of Hepatocellular Carcinoma; Prognostic Subtypes of Hepatocellular Carcinoma Redefined by Supervised Approaches; Prognostic Subtypes of Hepatocellular Carcinoma Uncovered by Unsupervised or Semi-supervised Approaches; Nontumor Genomic Signatures; Conclusion and Perspective; References; Chapter 7: Liquid Biopsy in Hepatocellular Carcinoma; Introduction; Circulating Tumor Cells
• Publisher Details: Cham : Humana Press
• Publication Date: 2019
• Extent: 1 online resource (365 pages)
• Subjects: 616.99/436; Liver -- Cancer; Carcinoma, Hepatocellular; Liver -- Cancer; Electronic books
• Languages: English
• ISBNs: 9783030215408; 3030215407
• Related ISBNs: 9783030215392
• Notes: Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.