Advancements of mass spectrometry in biomedical research. (2019)

• Record Type: Book
• Further Information: Note: Alisa G. Woods, Costel C. Darie, editors.
• Editors: Woods, Alisa G; Darie, Costel C
• Contents: 1. Mass Spectrometry for Proteomics-based Investigation2. MALDI profiling and applications in medicine3. Applications of Matrix-Assisted Laser Desorption Ionization In-Source Decay Mass Spectrometry4. Proteome imaging: from classic to modern mass spectrometry-based molecular histology5. Mass Spectrometry-Based Tissue Imaging of Small Molecules6. Sequencing Proteins from Bottom to Top: Combining Techniques for Full Sequence Analysis of Glucokinase7. Proteomics and non-proteomics approaches to study stable and transient protein-protein interactions8. Contribution of Mass spectrometry-based Proteomics to Discoveries in Developmental Biology9. Profiling optimal conditions for capturing EDEM proteins complexes in melanoma using mass spectrometry10. The Methods employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein–Protein Interactions (PPIs)11. Identification of post-translational modifications (PTMs) of proteins by mass spectrometry12. Sequence Variant and Post-translational Modification Analysis During Cell Line Selection via High-throughput Peptide Mapping13. Selective derivatization of hexahistidine-tagged recombinant proteins14. Investigation of Antibody-Drug Conjugates by Mass Spectrometry15. Mass Spectrometry- and Computational Structural Biology-Based Investigation of Proteins and Peptides16. Strategies for Membrane Protein Analysis by Mass Spectrometry17. The Potential for Ion Mobility in Pharmaceutical and Clinical Analyses18. Application of Ion Mobility Mass Spectrometry in Lipidomics19. Mass Spectrometry in Advancement of Redox Precision Medicine20. Applications for mass spectrometry in the study of ion channel structure and function21. Immuno – affinity Mass Spectrometry: A Novel Approaches with Biomedical Relevance22. Developing well-annotated species-specific protein databases using comparative proteogenomics23. Stoichiometry of heavy metal binding to peptides involved in Alzheimer's disease: mass spectrometric evidence24. Role of mass spectrometry in investigating a novel protein: the example of Tumor Differentiation Factor (TDF)25. Mass Spectrometry-Based Biomarkers in Drug Developmen26. Combinatorial Electrophoresis and Mass Spectrometry-Based Proteomics in Breast Milk for Breast Cancer Biomarker Discovery27. Proteomic approaches to dissect neuronal signalling pathways28. Mass Spectrometry for the Study of Autism and Neurodevelopmental Disorders29. Simplifying the proteome: Analytical strategies for improving peak capacity30. Exploration of nicotine metabolism in Paenarthrobacter nicotinovorans pAO1 by microbial proteomics31. Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) for Quantitative Proteomics32. Mass spectrometry based comparative proteomics using one dimensional and two dimensional SDS-PAGE of rat atria induced with obstructive sleep apnea33. 2D SDS PAGE in combination with western blotting and mass spectrometry is a robust method for protein analysis with many applications.34. Pulse SILAC approaches to the measurement of cellular dynamics35. Protein Biomarkers in Major Depressive Disorder: an Update36. A Pilot Exploratory Proteomics Investigation of Mental Fatigue and Mental Energy37. Metabolomics and biomarker discovery38. Analytical Methods for Mass Spectrometry-Based Metabolomics Studies39. Trends in analysis of cortisol and its derivatives40. Detection of biomedically relevant stilbenes from wines by mass spectrometry41. Mass spectrometry as a complementary approach for noncovalently bound complexes based on cyclodextrins42. Trends in glycolipid biomarker discovery in neurodegenerative disorders by mass spectrometry43. Non-targeted Screening in Environmental Monitoring Programs44. Mass Spectrometric DNA Adduct Quantification by Multiple Reaction Monitoring and its Future Use for the Molecular Epidemiology of Cancer45. Bottlenecks in proteomics: an update46. Recent Applications of Mass Spectrometry at Clarkson University Index.
• Edition: Second edition
• Publisher Details: Cham : Springer
• Publication Date: 2019
• Extent: 1 online resource (805 p.)
• Subjects: 572/.36; Mass spectrometry; Proteomics -- Methodology; Clinical biochemistry -- Methodology; Mass spectrometry; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783030159504; 3030159507
• Related ISBNs: 9783030159498
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed August 7, 2019)
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.