Bioactive lipids in health and disease. ([2019])

• Record Type: Book
• Further Information: Note: Andres Trostchansky, Homero Rubbo, editors.
• Editors: Trostchansky, Andres; Rubbo, Homero
• Contents: Intro; Preface; Contents; Part I: Structure, Characterization and Physicochemical Properties of Bioactive Lipids; 1: Diffusion and Transport of Reactive Species Across Cell Membranes; 1.1 Cellular Membranes; 1.2 Diffusion Across Membranes; 1.3 The Permeability Coefficient; 1.4 Interactions of Reactive Species with Membranes; 1.4.1 Oxygen; 1.4.2 Singlet Oxygen; 1.4.3 Nitric Oxide; 1.4.4 Nitrogen Dioxide; 1.4.5 Hydrogen Sulfide; 1.4.6 Peroxynitrite Anion and Peroxynitrous Acid; 1.4.7 Superoxide and Hydroperoxyl Radical; 1.4.8 Hydrogen Peroxide; 1.4.9 Hydroxyl Radical 1.5 Considerations About the Permeability of Membranes to Reactive SpeciesReferences; 2: Characterization of Hydroxy and Hydroperoxy Polyunsaturated Fatty Acids by Mass Spectrometry; 2.1 Introduction; 2.2 Fatty Acid Hydroperoxide Formation; 2.3 Hydroperoxide- and Hydroxy-Polyunsaturated Fatty Acids Analysis; 2.3.1 Characterization of Linoleic Acid Hydro(pero)xides; 2.3.2 Characterization of Arachidonic Acid Hydro(pero)xides; 2.3.3 Characterization of Eicosapentaenoic Acid Hydro(pero)xides; 2.3.4 Characterization of Docosahexaenoic Acid Hydro(pero)xides; 2.4 Conclusion; References 4: Diminishing Inflammation by Reducing Oxidant Generation: Nitrated Fatty Acid-Mediated Inactivation of Xanthine Oxidoreductase4.1 Xanthine Oxidoreductase (XOR); 4.2 Shortcomings Associated with Allo/Oxypurinol Inhibition of XOR; 4.3 Nitrated Fatty Acids; 4.4 OA-NO2 and LNO2 Inactivate XOR; 4.5 XOR-Endothelium Interaction Does not Affect Inactivation by OA-NO2; References; 5: Unfolded Protein Response: Cause or Consequence of Lipid and Lipoprotein Metabolism Disturbances?; 5.1 Introduction; 5.2 The Unfolded Protein Response 5.3 From the Unfolded Protein Response to Lipid Metabolism Disturbances5.4 From Lipotoxicity to Unfolded Protein Response; 5.5 Closing Remarks and Perspectives; References; Part III: Bioactive Lipids in Inflammatory and Cardiovascular Diseases; 6: Arachidonic Acid and Nitroarachidonic: Effects on NADPH Oxidase Activity; 6.1 Introduction; 6.2 Arachidonic Acid Metabolism in Macrophage Activation; 6.3 NADPH Oxidase 2 Activation; 6.4 Activation of NOX2 by Arachidonic Acid; 6.5 Inhibition of NOX2 by Nitroarachidonic Acid; 6.6 Summary; References
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2019
• Extent: 1 online resource
• Subjects: 599.93/5; Lipids; Bioactive compounds; Lipids -- Biotechnology; Electronic books
• Languages: English
• ISBNs: 9783030114886; 3030114880
• Related ISBNs: 3030114872; 9783030114879
• Notes: Note: Description based on online resource; title from digital title page (viewed on July 08, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.