Computing characterizations of drugs for ion channels and receptors using Markov models. (2016)

• Record Type: Book
• Further Information: Note: Aslak Tveito, Glenn T. Lines.
• Authors: Tveito, Aslak, 1961-; Lines, Glenn T
• Contents: Background : problem and methods -- One-dimensional calcium release -- Models of open and state blockers -- Properties of probability density functions -- Two-dimensional calcium release -- Computing theoretical drugs in the two-dimensional case -- Generalized systems governing probability density functions -- Calcium-induced calcium release -- Numerical drugs for calcium-induced calcium release -- A prototypical model of an ion channel -- Inactivated ion channels : extending the prototype model -- A simple model of the sodium channel -- Mutations affecting the mean open time -- The burst mode of the mutant sodium channel -- Action potentials : summing up the effect of loads of ion channels.
• Publisher Details: Switzerland : SpringerOpen
• Publication Date: 2016
• Extent: 1 online resource (xvi, 261 pages), illustrations (some color)
• Subjects: 571.6/4015118; Ion channels -- Effect of drugs on -- Mathematical models; Markov processes; Markov processes; Electronic books
• Languages: English
• ISBNs: 9783319300306; 3319300296; 9783319300290
• Related ISBNs: 331930030X; 9783319300290
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (SpringerLink, viewed April 26, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.