High-throughput metabolomics : methods and protocols /: methods and protocols. (2019)

• Record Type: Book
• Further Information: Note: Edited by Angelo D'Alessandro.
• Editors: D'Alessandro, Angelo
• Contents: Part I: Methods 1. Sample Preparation and Reporting Standards for Metabolomics of Adherent Mammalian Cells Sarah Hayton, Robert D. Trengove, and Garth L. Maker 2. High-Throughput Metabolomics: Isocratic and Gradient Mass Spectrometry-Based Methods Travis Nemkov, Julie A. Reisz, Sarah Gehrke, Kirk C. Hansen, and Angelo D'Alessandro 3. High-Throughput Metabolomics Based on Direct Mass Spectrometry Analysis in Biomedical Research Raúl González-Domínguez, Álvaro González-Domínguez, Carmen Segundo, Mónica Schwarz, Ana Sayago, Rosa María Mateos, Enrique Durán-Guerrero, Alfonso María Lechuga-Sancho, and Ángeles Fernández-Recamales 4. Traveling Wave Ion Mobility Mass Spectrometry: Metabolomics Applications Giuseppe Paglia and Giuseppe Astarita 5. CE-MS for Metabolomics: A Comparison with Other Techniques Joanna Godzien, Antonia Garcia, Angeles López-Gonzalvez, and Coral Barbas Part II: Lipidomics 6. Overview of Lipid Mass Spectrometry and Lipidomics Simona Zarini, Robert M. Barkley, Miguel A. Gijón, and Robert C. Murphy 7. LC-MS/MS-MRM-Based Targeted Metabolomics for Quantitative Analysis of Polyunsaturated Fatty Acids and Oxylipins Xiaoyun Fu, Mikayla Anderson, Yi Wang, and James C. Zimring 8. Untargeted and Semi-Targeted Lipid Analysis of Biological Samples Using Mass Spectrometry-Based Metabolomics Julie A. Reisz, Connie Zheng, Angelo D'Alessandro, and Travis Nemkov 9. HPLC-MS/MS Methods for Diacylglycerol and Sphingolipid Molecular Species in Skeletal Muscle Kathleen A. Harrison and Bryan C. Bergman Part III: Metabolomics of Animal and Plant Models 10. Quantification of D- and L-2-Hydroxyglutarate in Drosophila melanogaster Tissue Samples Using Gas Chromatography-Mass Spectrometry Hongde Li and Jason M. Tennessen 11. Comprehensive LC-MS-Based Metabolite Fingerprinting Approach for Plant and Fungal-Derived Samples Kirstin Feussner and Ivo Feussner 12. Untargeted Metabolomics of Plant Leaf Tissues Federica Gevi, Giuseppina Fanelli, Lello Zolla, and Sara Rinalducci Part IV: Tracing Experiments and Metabolic Flux Analysis 13. Analysis of Arginine Metabolism Using LC-MS and Isotopic Labeling Gretchen L. Seim, Emily C. Britt, and Jing Fan 14. Quantifying Intermediary Metabolism and Lipogenesis in Cultured Mammalian Cells Using Stable Isotope Tracing and Mass Spectrometry Thekla Cordes and Christian M. Metallo 15. Insights into Dynamic Network States Using Metabolomic Data Reihaneh Mostolizadeh, Andreas Dräger, and Neema Jamshidi 16. Analysis of Endothelial Fatty Acid Metabolism Using Tracer Metabolomics Joanna Kalucka, Bart Ghesquière, Sarah-Maria Fendt, and Peter Carmeliet 17. Using Stable Isotope Tracers for Metabolic Pathway Analysis Sara Violante, Tiffany H. Thomas, and Justin R. Cross Part V: Data Processing in Metabolomics 18. Data Processing for GC-MS and LC-MS-Based Untargeted Metabolomics Linxing Yao, Amy M. Sheflin, Corey D. Broeckling, and Jessica E. Prenni 19. El-MAVEN: A Fast, Robust, and User-Friendly Mass Spectrometry Data Processing Engine for Metabolomics Shubhra Agrawal, Sahil Kumar, Raghav Sehgal, Sabu George, Rishabh Gupta, Surbhi Poddar, Abhishek Jha, and Swetabh Pathak 20. Pre-Analytic Considerations for Mass Spectrometry-Based Untargeted Metabolomics Data Dominik Reinhold, Harrison Pielke-Lombardo, Sean Jacobson, Debashis Ghosh, and Katerina Kechris Part VI: Metabolic Measurements with Techniques Orthogonal to Mass Spectrometry 21. Temporal Metabolite, Ion, and Enzyme Activity Profiling Using Fluorescence Microscopy and Genetically-Encoded Biosensors Douglas A. Chapnick, Eric Bunker, Xuedong Liu, and William M. Old 22. Microplate Assays for Spectrophotometric Measurement of Mitochondrial Enzyme Activity Rachel C. Janssen and Kristen E. Boyle 23. Quantitative NMR-Based Metabolomics on Tissue Biomarkers and Its Translation into In Vivo Magnetic Resonance Spectroscopy Natalie J. Serkova, Denise M. Davis, Jenna Steiner, and Rajesh Agarwal Part VII: Towards Personalized Metabolomics 24. Metabolomic Applications in Radiation Biodosimetry Evagelia C. Laiakis 25. Metabolomics Analyses to Investigate the Role of Diet and Physical Training Pol Herrero, Miguel Ángel Rodriguez, Mª Rosa Ras, Antoni del Pino, Lluís Arola, and Núria Canela 26. Blood Biomarkers in Sports Medicine and Performance and the Future of Metabolomics Iñigo San Millán 27. Personalized Metabolomics David P. Marciano and Michael P. Snyder.
• Publisher Details: New York, NY : Humana Press
• Publication Date: 2019
• Extent: 1 online resource (xv, 459 pages), illustrations (some color)
• Subjects: 572/.4; Metabolites -- Laboratory manuals; Metabolism -- Disorders -- Laboratory manuals; Bioinformatics -- Laboratory manusl; Electronic books
• Languages: English
• ISBNs: 9781493992362; 1493992368
• Related ISBNs: 9781493992355
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed June 21, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.