Advances in Computational Toxicology : Methodologies and Applications in Regulatory Science /: Methodologies and Applications in Regulatory Science. (2019)

• Record Type: Book
• Further Information: Note: Huixiao Hong, editor.
• Editors: Hong, Huixiao
• Contents: Computational Toxicology Promotes Regulatory Science -- Tasks, Major Challenges and Emerging Modelling Methods for Computational Toxicology -- Xenobiotic Metabolism by Cytochrome P450s: Insights Gained from Molecular Simulations -- Applications of Molecular Modeling to Probe the Mechanism of Endocrine Disruptor Action -- Mixture Toxicity -- Towards reproducible in silico practice via OpenTox -- Combining Machine Learning and Multilayer Networks for Toxicity Prediction -- Matrix and tensor factorization for toxicity modelling -- Network-based In Silico Assessment of Drug Cardiotoxicity -- Mode-of-action-guided chemical toxicity prediction: A novel in silico approach for predictive toxicology -- Machine learning methods for toxicity analysis -- Predictive modeling of Tox21 data -- The NTP DrugMatrix Toxicogenomics Database and Analysis Tool -- Applications of Computational Toxicology for Risk Assessment of Food Ingredients and Indirect Food Additives -- In silico prediction of the point of departure (POD) with high throughput data -- The application of topic modeling on drug safety signal detection and analysis -- Molecular dynamics simulations and applications in computational toxicology -- Computational modeling for prediction of drug-induced liver injury in humans -- Genomics in vitro to in vivo extrapolation (GIVIVE) for drug safety evaluation.
• Publisher Details: Cham : Springer
• Publication Date: 2019
• Extent: 1 online resource (416 pages)
• Subjects: 615.9; Toxicology -- Data processing; Toxicity testing; Electronic books
• Languages: English
• ISBNs: 9783030164430; 3030164438
• Related ISBNs: 9783030164423
• Notes: Note: Description based upon print version of record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.