RNA interference and cancer therapy : methods and protocols /: methods and protocols. (2019)

• Record Type: Book
• Further Information: Note: Edited by Lekha Dinesh Kumar.
• Editors: Dinesh Kumar, Lekha
• Contents: 1. siRNA Library Screening to Identify Complementary Therapeutic Pairs in Triple Negative Breast Cancer Cells Bindu Thapa, Remant Bahadur KC, and Hasan Uludağ 2. In Vitro Evaluation of Candidate Gene Targets for Cancer Therapy Xing Fei Tan, Wei Xuan Teo, and George W. Yip 3. siRNA-Based Drug Targeting Human Bcl-xL against Cancers Yoshifumi Takei 4. Relative Quantification of siRNA Strand Loading into Ago2 for Design of Highly-Active siRNAs Phillip A. Angart, Kwasi Adu-Berchie, Rebecca J. Carlson, Daniel B. Vocelle, Christina Chan, and S. Patrick Walton 5. VEGFA Gene Silencing in CXCR4-Expressing Cells via siRNA Delivery by Means of Targeted Peptide Carrier Anna A. Egorova, Marianna A. Maretina, and Anton V. Kiselev 6. Design Strategy to Access siRNA-Encapsulating DNA 'Nanosuitcases' that Can Conditionally Release their Cargo Katherine E. Bujold, Hassan H. Fakih, and Hanadi F. Sleiman 7. Combinatorial siRNA Polyplexes for Receptor Targeting Dian-Jang Lee and Ernst Wagner 8. Synthesis of Doxorubicin and miRNA Stimuli-Sensitive Conjugates for Combination Therapy Daniel F. Costa, Can Sarisozen, and Vladimir P. Torchilin 9. Minicell-Based Targeted Delivery of shRNA to Cancer Cells: An Experimental Protocol Mehul Jivrajani and Manish Nivsarkar 10. Targeted Delivery of miRNA Antagonists to Myeloid Cells In Vitro and In Vivo Yu-Lin Su, Piotr Swiderski, Guido Marcucci, and Marcin Kortylewski 11. Systemic Modulation of Lymphocyte Subsets Using siRNAs Delivered via Targeted Lipid Nanoparticles Inbal Hazan-Halevy, Daniel Rosenblum, Srinivas Ramishetti, and Dan Peer 12. Targeting Cancer with Peptide RNAi Nanoplexes A. James Mixson, Qixin Leng, Szu-Ting Chou, and Martin C. Woodle 13. Preparation of a Carrier to Achieve In Vivo Delivery of siRNA: The Example of Chitosan-Coated Poly(isobutylcyanoacrylate) Nanoparticles Christine Vauthier 14. Monoclonal Antibody-Conjugated Dendritic Nanostructures for siRNA Delivery Hitesh Kulhari, Ashok K. Jangid, and David J. Adams 15. Synthesis of Gold Nanoparticles for Gene Silencing Claudia Tortiglione and Jesus M. de la Fuente 16. Design of Eco-Friendly Gold Nanoparticles for Cancer Treatment Deep Pooja and Ramakrishna Sistla 17. 64Cu-Labeled Aptamers for Tumor-Targeted Radionuclide Delivery Lei Kang, Zachary T. Rosenkrans, and Weibo Cai 18. Silencing PRDM14 via Oligonucleotide Therapeutics Suppresses Tumorigenicity and Metastasis of Breast Cancer Hiroaki Taniguchi and Kohzoh Imai 19. Bio-Drug Suppresses Breast and Colorectal Cancer in Murine Models Syed Sultan Beevi, Naveen Kumar Tangudu, Vinod Kumar Verma, and Lekha Dinesh Kumar 20. Combinatorial Nanoparticle Delivery of siRNA and Antineoplastics for Lung Cancer Treatment Rebaz Ahmed, Narsireddy Amreddy, Anish Babu, Anupama Munshi, and Rajagopal Ramesh 21. Bioconjugated Gold Nanoparticles Enhance siRNA Delivery in Prostate Cancer Cells Kamil Rahme, Jianfeng Guo, and Justin D. Holmes 22. Vaginal Suppositories with siRNA and Paclitaxel-Incorporated Solid Lipid Nanoparticles for Cervical Cancer: Preparation and In Vitro Evaluation Gülay Büyükköroğlu, Behiye Şenel, and Evrim Yenilmez 23. The Use of Star Polymer Nanoparticles for the Delivery of siRNA to Mouse Orthotopic Pancreatic Tumor Models Joshua A. McCarroll, George Sharbeen, Maria Kavallaris, and Phoebe A. Phillips 24. Microfluidic Assembly of siRNA-Loaded Micelleplexes for Tumor Targeting in an Orthotopic Model of Ovarian Cancer Daniel P. Feldmann, Steven Jones, Kirk Douglas, Anthony F. Shields, and Olivia M. Merkel 25. Synthesis, Physico-Chemical, and Biological Evaluation of Spherical Nucleic Acids for RNAi-Based Therapy in Glioblastoma Serena Tommasini-Ghelfi, Andrew Lee, Chad A. Mirkin, and Alexander H. Stegh 26. Folate-Decorated Polyamidoamine Dendrimer Nanoparticles for Head and Neck Cancer Gene Therapy Leyuan Xu and Hu Yang.
• Publisher Details: New York, NY : Humana Press
• Publication Date: 2019
• Extent: 1 online resource (xiii, 416 pages), illustrations (some color)
• Subjects: 572.8/8; RNA interference -- Laboratory manuals; Cancer -- Gene therapy -- Laboratory manuals; Electronic books
• Languages: English
• ISBNs: 9781493992201; 1493992201
• Related ISBNs: 9781493992195
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed June 17, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.