Textbook of clinical trials in oncology : a statistical perspective /: a statistical perspective. ([2019])

• Record Type: Book
• Further Information: Note: Edited by Susan Halabi, Stefan Michiels.
• Editors: Halabi, Susan; Michiels, Stefan
• Contents: Section I Introduction Introduction to Clinical Trials - Susan Halabi, Stefan Michiels Section II General Issues Selection of Endpoints - Katherine S Panageas and Andrea Knezevic Section III Early Development Innovative Phase I Trials - Cody Chiuzan and Nathaniel O’Connell Section IV Middle Development Current Issues in Phase II Cancer Clinical Trials - Sin-Ho Jung Design and Analysis of Immunotherapy Clinical Trials - Megan Othus Adaptive Designs - William T. Barry Section V Late Phase Clinical Trials Sample Size Calculations for Phase III Trials in Oncology - Koji Oba, Aye Kuchiba Non-inferiority Trial - Keyue Ding, Chris O’Callaghan Design of Multi-arm, Multi-stage Trials in Oncology - James Wason Multiple Comparisons, Multiple Primary Endpoints and Subpopulation Analysis - Ekkehard Glimm, Dong Xi, Paul Gallo Cluster Randomized Trials - Catherine M. Crespi Statistical Monitoring of Safety and Efficacy - Jay Herson, Chen Hu Section VI Personalized Medicine Biomarker-Based Phase II and III Clinical Trials in Oncology - Shigeyuki Matsui, Masataka Igeta, Kiichiro Toyoizumi Genomic Biomarker Clinical Trial Designs - Richard Simon Trial designs for rare diseases and small samples in oncology - Robert A. Beckman, Cong Chen, Martin Posch and Sarah Zohar Statistical Methods for Biomarker and Subgroup Evaluation in Oncology Trials - Ilya Lipkovich, Alex Dmitrienko, Bohdana Ratitch Developing and Validating Prognostic Models of Clinical Outcomes - Susan Halabi, Lira Pi, and Chen-Yen Lin High-Dimensional Penalized Regression Models in Time-to-Event Clinical Trials - Federico Rotolo, Nils Ternes, Stefan Michiels Sequential Multiple Assignment Randomized Trials - Kelly Speth, Kelley M. Kidwell Section VII Advanced Topics Assessing the value of surrogate endpoints - Xavier Paoletti, Federico Rotolo, Stefan Michiels Competing Risks - Aurelien Latouche, Gang Li, Qing Yang Cure models in cancer clinical trials - Catherine Legrand, Aurelie Bertrand Interval Censoring - Yuan Wu Methods for analysis of trials with changes from randomised treatment - Nicholas R. Latimer and Ian R. White The analysis of adverse events in randomized clinical trials - Jan Beyersmann, Claudia Schmoor Analysis of quality of life outcomes in oncology trials - Stephen Walters Missing Data - Stephanie Pugh, James J. Dignam, Juned Siddique
• Publisher Details: Boca Raton, Florida : CRC Press
• Publication Date: 2019
• Extent: 1 online resource
• Subjects: 616.99/400727; Cancer -- Research -- Statistical methods; Clinical trials -- Statistical methods; HEALTH & FITNESS / Diseases / General; MEDICAL / Clinical Medicine; MEDICAL / Diseases; MEDICAL / Evidence-Based Medicine; MEDICAL / Internal Medicine; MEDICAL / Biostatistics; MEDICAL / Pharmacology; MATHEMATICS / Probability & Statistics / General; Electronic books
• Languages: English
• ISBNs: 9781315112084; 1315112086; 9781351620970; 1351620975; 9781351620963; 1351620967; 9781351620956; 1351620959
• Related ISBNs: 9781138083776; 1138083771
• Notes: Note: Includes bibliographical references and index.; Note: Print version record.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.