Target organ toxicology in Caenorhabditis elegans. ([2019])

• Record Type: Book
• Further Information: Note: Dayong Wang.
• Authors: Wang, Dayong
• Contents: Intro; Preface; Contents; Chapter 1: Protective Responses of Different Organs to Environmental Toxicants or Stresses; 1.1 Introduction; 1.2 Protective Responses to Environmental Toxicants or Stresses in the Intestine; 1.2.1 Superoxide Dismutase (SOD) Proteins; 1.2.2 MTL-1 and MTL-2; 1.2.3 Heat Shock Proteins (HSPs); 1.2.4 PMK-1, SKN-1/Nrf, and GST-4; 1.2.5 Transcriptional Factor DAF-16; 1.2.6 Antimicrobial Proteins; 1.2.7 Mitochondrial Unfolded Protein Response (UPR); 1.2.8 Endoplasmic Reticulum (ER) UPR; 1.2.9 Autophagy 1.3 Protective Responses to Environmental Toxicants or Stresses in Epidermis1.3.1 Antimicrobial Proteins; 1.3.2 Autophagy; 1.4 Protective Responses to Environmental Toxicants or Stresses in Neurons; 1.4.1 SKN-1/Nrf; 1.4.2 JNK Signaling; 1.4.3 ERK Signaling; 1.4.4 Antimicrobial Proteins; 1.4.5 Autophagy; 1.5 Protective Responses to Environmental Toxicants or Stresses in Muscle; 1.6 Perspectives; References; Chapter 2: Avoidance Behavior of Nematodes to Environmental Toxicants or Stresses; 2.1 Introduction 2.2 Neurons Involved in the Regulation of Avoidance Behavior to Environmental Toxicants or Stress2.2.1 ASH Sensory Neurons; 2.2.1.1 Involvement of ASH Sensory Neurons in Response to Environmental Toxicants or Stresses; 2.2.1.2 Molecular Basis for ASH Sensory Neurons in Response to Environmental Toxicants or Stresses; 2.2.1.2.1 G Proteins; 2.2.1.2.2 Seven-Transmembrane Protein DCAR-1; 2.2.1.2.3 Neurotransmitter Signals; 2.2.2 ADL Sensory Neurons; 2.2.2.1 Involvement of ADL Sensory Neurons in Response to Environmental Toxicants or Stresses 2.2.2.2 Molecular Basis for ADL Sensory Neurons in Response to Environmental Toxicants or Stresses2.2.3 ASK Sensory Neurons; 2.2.4 ASJ Sensory Neurons; 2.2.4.1 Involvement of ASJ Sensory Neurons in Response to Environmental Toxicants or Stresses; 2.2.4.2 Molecular Basis for ASJ Sensory Neurons in Response to Environmental Toxicants or Stresses; 2.2.5 ADF Sensory Neurons; 2.2.6 ASI Sensory Neurons; 2.2.7 AWB Sensory Neurons; 2.2.8 AWC Sensory Neurons; 2.2.9 BAG Sensory Neurons; 2.2.9.1 Involvement of BAG Sensory Neurons in Response to Environmental Toxicants or Stresses 2.2.9.2 Molecular Basis for BAG Sensory Neurons in Response to Environmental Toxicants or Stresses2.2.10 OLL Sensory Neurons; 2.2.11 Interneurons; 2.3 Neuronal Circuit for the Avoidance Behavior to Environmental Toxicants or Stresses and the Underlying Molecular Basis; 2.3.1 ASI-ADF-ASH and ASH-RIC-ASI Neuronal Circuits; 2.3.1.1 ASI-ADF-ASH Neuronal Circuit; 2.3.1.2 ASH-RIC-ASI Neuronal Circuit; 2.3.1.3 Cross-Inhibitory Neural Circuitry Between ASHs and ASIs; 2.3.2 ADL-AIB Neuronal Circuit; 2.3.3 ASJ-RIM/RIC Neuronal Circuit; 2.3.4 AWB-AIZ/RMG Neuronal Circuit; 2.3.5 OLL-RMG Neuronal Circuit
• Publisher Details: Singapore : Springer
• Publication Date: 2019
• Extent: 1 online resource
• Subjects: 595.182; Caenorhabditis elegans -- Toxicology; Target organs (Anatomy); SCIENCE / Life Sciences / Zoology / General; Target organs (Anatomy); Pharmacology/Toxicology; Cell Biology; Invertebrates; Electronic books
• Languages: English
• ISBNs: 9789811360107; 9811360103; 9789811360114; 9811360111
• Related ISBNs: 9789811360091; 981136009X
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (EBSCO, viewed February 14, 2019).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.