Chromosome translocation. ([2018])

• Record Type: Book
• Further Information: Note: Yu Zhang, editor.
• Editors: Zhang, Yu
• Contents: Historical and clinical perspectives on chromosomal translocations / Ellen S. Wilch, Cynthia C. Morton -- Induction of chromosomal translocations with CRISPR-Cas9 and other nucleases: understanding the repair mechanisms that give rise to translocations / Erika Brunet, Maria Jasin -- Dynamics of double-strand breaks: implications for the formation of chromosome translocations / Henrike Johanna Gothe, Vera Minneker, Vassilis Roukos -- The CRISPR/Cas9 system as a tool to engineer chromosomal translocation in vivo / Taek-Chin Cheong, Rafael B. Blasco, Roberto Chiarle -- Generation of genomic alteration from cytidine deamination / Xiaojing Liu, Fei-Long Meng -- The role for the DSB response pathway in regulating chromosome translocations / Rajib Ghosh, Debamitra Das, Sonia Franco -- Telomeres and chromosomal translocations / Duncan M. Baird, Eric A. Hendrickson -- 3D genome organization influences the chromosome translocation pattern / Rachel Patton McCord, Adayabalam Balajee -- The role of chromosome deletions in human cancers / Mei Chen, Yi Yang, Yu Liu, Chong Chen -- Processing-challenges generated by clusters of DNA double-strand breaks underpin increased effectiveness of high-LET radiation and chromothripsis / Emil Mladenov, Janapriya Saha, George Iliakis.
• Publisher Details: Singapore : Springer
• Publication Date: 2018
• Copyright Date: 2018
• Extent: 1 online resource (v, 168 pages), illustrations (some color)
• Subjects: 572.8/77; Translocation (Genetics); SCIENCE -- Life Sciences -- Biochemistry; Translocation (Genetics); Cell Biology; Translocation, Genetic -- physiology; Electronic books
• Languages: English
• ISBNs: 9789811305931; 9811305935
• Related ISBNs: 9789811305924; 9811305927
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (SpringerLink, viewed July 3, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.