Dengue and Zika : control and antiviral treatment strategies /: control and antiviral treatment strategies. (2018)

• Record Type: Book
• Further Information: Note: Rolf Hilgenfeld, Subhash G. Vasudevan, editors.
• Editors: Hilgenfeld, R (Rolf); Vasudevan, Subhash
• Other Names: Tofo Advanced Study Week, 2nd
• Contents: Arboviruses on the rise -- Historical perspective of arboviruses in Mozambique and its implication for current and future epidemics -- Reliable serological testing for the diagnosis of emerging infectious diseases -- Flaviviral RNA structures and their role in replication and immunity -- The molecular specificity of the human antibody response to dengue virus infections -- Structures of Zika virus E & NS1: relations with virus infection and host immune responses -- Plugging the leak -- is dengue a case of aseptic shock with NS1 at its center -- Entry & NS1 as drug targets -- The dengue virus replication complex: from RNA replication to protein-protein interactions to evasion of innate immunity -- Crystal structure of Zika virus NS2B-NS3 protease -- The transactions of NS3 and NS5 in Dengue viral RNA replication -- Establishment and application of flavivirus replicons -- Strategies towards protease inhibitors for emerging flaviviruses -- Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent RNA polymerase from fragment screening and structure-guided design -- Nuclear cytoplasmic trafficking of dengue non-structural protein 5 as a target for antivirals -- Animal models for dengue and Zika vaccine development -- Understanding the human T cell response to dengue virus -- Regulation and function of NK and T cells during dengue virus infection and vaccination -- Structural insights into the broad-spectrum antiviral target Endoplasmic Reticulum alpha glucosidase II -- Mechanisms of antiviral activity of iminosugars against dengue virus -- Countering Zika virus: the USAMRIID response -- Dengue antiviral development: a continuing journey -- An industry perspective on dengue drug discovery and development -- The use of wolbachia by the Eliminate Dengue program to interrupt transmission of Aedes aegypti transmitted viruses -- Seroepidemiological studies of arboviruses in Africa.
• Publisher Details: Singapore : Springer
• Publication Date: 2018
• Copyright Date: 2018
• Extent: 1 online resource (375 pages)
• Subjects: 616.9/185; Dengue -- Congresses; Zika virus infection -- Congresses; Dengue Virus; Zika Virus; Aedes; Dengue; Zika Virus Infection; Dengue; Zika virus infection; Congress; Conference papers and proceedings
• Languages: English
• ISBNs: 9789811087271
• Related ISBNs: 9789811087264
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.