The role of water in ATP hydrolysis energy transduction by protein machinery. (2018)

• Record Type: Book
• Further Information: Note: Makoto Suzuki, editor.
• Editors: Suzuki, Makoto
• Contents: Intro; Preface; Contents; Basis of ATP Hydrolysis Reaction; 1 Free Energy Analyses for the ATP Hydrolysis in Aqueous Solution by Large-Scale QM/MM Simulations Combined with a Theory of Solutions; 1.1 Introduction; 1.2 Theoretical Method; 1.2.1 Real-Space Grid Approach; 1.2.2 QM/MM Approach; 1.2.3 QM/MM-ER Method; 1.2.4 Free Energy of Hydrolysis; 1.3 Computational Details; 1.4 Results and Discussion; 1.5 Conclusion; References; 2 Role of Metal Ion Binding and Protonation in ATP Hydrolysis Energetics; Abstract; 2.1 Introduction; 2.2 Theory; 2.3 Results and Discussions. 2.3.1 ATP Hydrolysis Energetics at pH 7.02.3.2 Apparent pKa's for ATP, ADP, and Pi; 2.3.3 Apparent pKMg's for ATP, ADP, and Pi; 2.3.4 Effect of Other Metal Ions on ATP Hydrolysis Energetics; 2.4 Conclusions; References; 3 Spatial Distribution of Ionic Hydration Energy and Hyper-Mobile Water; Abstract; 3.1 Introduction; 3.2 Hydration Measurement by Dielectric Relaxation Spectroscopy; 3.2.1 Preparation of Aqueous Solutions of Salts; 3.2.2 Dielectric Spectroscopy: Experimental Method; 3.2.3 Dielectric Spectroscopy: Data Analysis; 3.2.4 Hydration Properties of Salt Solutions. 4 Theoretical Studies of Strong Attractive Interaction Between Macro-anions Mediated by Multivalent Metal Cations and Related Association Behavior: Effective Interaction Between ATP-Binding Proteins Can Be Regulated by HydrolysisAbstract; 4.1 Introduction; 4.2 Condensation of Acidic Proteins by Multivalent Metal Cations; 4.3 Integral Equation Theory for Liquids; 4.4 Potential of Mean Force (PMF) Between Macro-anions; 4.5 Association and Dissociation Model Mechanism for the Engine of a Protein Linear Motor; 4.6 Summary; References. 5 Statistical Mechanical Integral Equation Approach to Reveal the Solvation Effect on Hydrolysis Free Energy of ATP and Its AnalogueAbstract; 5.1 Introduction; 5.2 The 3D-RISM Theory; 5.3 Hybrid 3D-RISM and Electronic Structure Theories; 5.4 Hydrolysis of Pyrophosphate; 5.5 Hydrolysis of ATP; 5.6 Summary; References; 6 A Solvent Model of Nucleotide-Protein Interaction-Partition Coefficients of Phosphates Between Water and Organic Solvent; Abstract; 6.1 Introduction; 6.2 Measurement of Partition Coefficients of Phosphoric Compounds Between Water and Alkylamine/Octanol.
• Publisher Details: Singapore : Springer
• Publication Date: 2018
• Extent: 1 online resource
• Subjects: 572/.475; Adenosine triphosphate; Hydrolysis; SCIENCE -- Life Sciences -- Biochemistry; Adenosine triphosphate; Hydrolysis; Chemistry; Physical Chemistry; Protein-Ligand Interactions; Biological and Medical Physics, Biophysics; Electronic books
• Languages: English
• ISBNs: 9789811084591; 9811084599
• Related ISBNs: 9789811084584; 9811084580
• Notes: Note: Online resource; title from PDF title page (SpringerLink, viewed May 14, 2018).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.