Protein modifications in pathogenic dysregulation of signaling. ([2015])

• Record Type: Book
• Further Information: Note: Jun-ichiro Inoue, Mutsuhiro Takekawa, editors.
• Editors: Inoue, Jun-ichiro; Takekawa, Mutsuhiro
• Contents: Preface -- Part I Novel Analytical Procedures for Signal Transduction -- 1 Phosphoproteomics-based Network Analysis of Cancer Cell Signaling Systems (Hiroko Kozuka-Hata and Masaaki Oyama) -- 2 Phos-tag-based Affinity Chromatography Techniques for Enrichment of the Phosphoproteome (Eiji Kinoshita, Emiko Kinoshita-Kikuta, and Tohru Koike) -- 3 Visualization of Intracellular Signaling with Fluorescence Resonance Energy Transfer-based Biosensors (Kazuhiro Aoki) -- 4 Technology of Wheat Cell-free Based Protein Array for Biochemical Analyses of Protein Kinases and Ubiquitin E3 Ligases (Hirotaka Takahashi, Keiichirou Nemoto, Ramadan Abdelaziz, Atsushi Uematsu, and Tatsuya Sawasaki) -- Part II Mathematical Simulation of Signal Transduction -- 5 Potential Roles of Spatial Parameters in the Regulation of NF-?B Oscillations, as Revealed by Computer Simulations (Daisuke Ohshima, Jun-ichiro Inoue, and Kazuhisa Ichikawa) -- 6 Stochastic Simulation of Stress Granules (Daisuke Ohshima, Kyoko Arimoto-Matsuzaki, Taichiro Tomida, Mutsuhiro Takekawa, and Kazuhisa Ichikawa) -- 7 Temporal Coding of Insulin Signaling (Hiroyuki Kubota and Shinya Kuroda) -- Part III Structural Analysis of Signal Transduction -- 8 Structural Biology of Protein Post-transcriptional Modifications and Cellular Signaling (Kazuki Kato, Hiroshi Nishimasu, Ryohei Ishii, Osamu Nureki, and Ryuichiro Ishitani) -- 9 Structural Basis for the Signal Initiation by TNF and TNFR (Teruya Nakamura, Yohei Mukai, Yasuo Tsutsumi, and Yuriko Yamagata) -- 10 Regulation of NF-?B Pathway by Linkage-specific Ubiquitin-binding Domains (Yusuke Sato) -- Part IV Regulation of Signal Transduction by Post-translational Modifications and Its Pathogenic Dysregulation -- 11 NF-?B Signaling and Lymphoid Malignancies (Shoji Yamaoka) -- 12 Ubiquitination-mediated NF-?B Regulation in Inflammatory Response (Fuminori Tokunaga) -- 13 NF-?B Signaling in Osteoclastogenesis (Yuu Taguchi, Jin Gohda, and Jun-ichiro Inoue) -- 14 Mitogen-activated Protein Kinase Signaling and Cancer (Mutsuhiro Takekawa and Yuji Kubota) -- 15 Critical Roles of the AKT Substrate Girdin in Disease Initiation and Progression (Atsushi Enomoto, Liang Weng, and Masahide Takahashi) -- 16 Protein Modifications Pace the Circadian Oscillation of Biological Clocks (Hikari Yoshitane and Yoshitaka Fukada) -- 17 Keap1-Nrf2 Regulatory System and Cancer (Keiko Taguchi and Masayuki Yamamoto) -- 18 Actin Filament Formation in Myofibrils and Cell Protrusions Regulated by Signal Transduction (Takeshi Endo and Kazunori Takano) -- 19 Molecular Signaling and its Pathogenic Alterations in Neuromuscular Junction Formation and Maintenance (Ryo Ueta and Yuji Yamanashi) -- 20 Post-translational Modification of Tcf/Lef: New Insights into the Regulation of Wnt/?-catenin Signaling (Tohru Ishitani) -- BM Index.
• Publisher Details: Tokyo : Springer
• Publication Date: 2015
• Extent: 1 online resource
• Subjects: 572; Post-translational modification; Cellular signal transduction; Proteins -- Research; Cytology; Biochemistry; SCIENCE -- Life Sciences -- Biochemistry; Biochemistry; Cellular signal transduction; Cytology; Post-translational modification; Proteins -- Research; Biochemistry; Chemistry; Physical Sciences & Mathematics; Life Sciences; Protein Science; Cell Biology; Cancer Research; Protein Processing, Post-Translational; Electronic books; Electronic books
• Languages: English
• ISBNs: 9784431555612; 4431555617; 4431555609; 9784431555605
• Related ISBNs: 9784431555605
• Notes: Note: Includes bibliographical references and index.; Note: Vendor-supplied metadata.
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• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.