Cardiorespiratory Fitness in Cardiometabolic Diseases : Prevention and Management in Clinical Practice /: Prevention and Management in Clinical Practice. ([2019])

• Record Type: Book
• Further Information: Note: Editors, Peter Kokkinos and Puneet Narayan.
• Editors: Kokkinos, Peter; Narayan, Puneet
• Contents: Intro; Preface; Contents; Contributors; 1: Physical Activity, Cardiorespiratory Fitness, and Health: A Historical Perspective; Introduction; Physical Activity and Health Connection; Physical Activity in the United States; Physical Activity, Exercise Capacity, and Health; A Call to Action; Final Note; References; 2: Exercise, Gene Regulation, and Cardiometabolic Disease; Introduction; Gene Regulation; Transcription Factor Binding; Epigenetic Control: Histone Modifications; Epigenetic Control: DNA Methylation; miRNA; Gene Regulation in CMD; Transcription Factors and Co-regulators Transgenerational EpigeneticsInflammation and CMD; miRNA and CMD; Treatments for CMD to Alter Gene Expression; Gene Regulation with Exercise; Inflammation and Exercise; miRNA; Variability in Training Response; Conclusions; References; 3: Exercise and the Mitochondria; Introduction; The Magical Mitochondria; Heart Muscle Mitochondria; Mitochondrial Replication, Transcription, and Biogenesis; Replication; Transcription; Biogenesis; Mitochondrial Medicine; Mitochondrial Disorders; Mitochondrial Dysfunction; Aging and Longevity in Connection to Mitochondria Epigenetic Modifications of the MitochondriaExercise Effect on Mitochondria; Interventional Evidence and Mechanisms of Exercise-Induced Changes Coupled to the Mitochondria; Clinical and Public Health Relevance; Conclusion and Future Directions; References; 4: Effect of Exercise on Adult Stem Cells; Introduction; Adult Stem Cells Are Influenced by Exercise; Effect of Exercise on Endothelial Progenitor Cells (EPCs) and Mesenchymal Stromal Cells (MSCs); Effects on EPCs; Effects on MSC; Conclusion; References; 5: Exercise Metabolism in Health and Disease; Exercise Metabolism: An Overview Muscle Fiber TypesEnergy Substrates; ATP; Phosphocreatine (PCr); Glycogen; Lipids; Metabolic Pathways; Anaerobic Metabolism During Exercise; The ATP-PCr System; Glycolysis; Regulation of Anaerobic Pathways; Lactate Metabolism; Lactate Threshold: How Is It Affected by Fitness?; Can the Lactate Threshold Be Altered?; Aerobic Metabolism During Exercise; Carbohydrate Metabolism; Regulation of Hepatic Glucose Production; Regulation of Muscle Glucose Uptake; Cross Talk Between Skeletal Muscle and Liver Metabolism in Exercise; Fat Metabolism; Regulation of Muscle Fat Metabolism Proteins as an Energy Source During ExerciseFactors Determining Substrate Preference During Exercise; Sex-Related Differences in Substrate Preference During Exercise; Cardiac Metabolism During Exercise; Metabolism of Energy Substrate in Heart During Exercise; Glucose; Free Fatty Acids; Ketone Bodies; Amino Acids; Preferred Substrate for Energy Needs of the Heart During Exercise; Molecular Mechanisms of Exercise-Induced Metabolic Adaptations in Cardiac Muscle; Future Considerations of Cardiac Metabolism; Exercise-Induced Chronic Metabolic Adaptations; Hormonal Regulation of Exercise Metabolism
• Publisher Details: Cham, Switzerland : Springer
• Publication Date: 2019
• Extent: 1 online resource
• Subjects: 616.1; Cardiovascular system -- Diseases -- Prevention; Metabolism -- Disorders -- Prevention; Exercise -- Health aspects; Cardiopulmonary system; HEALTH & FITNESS / Diseases / General; MEDICAL / Clinical Medicine; MEDICAL / Diseases; MEDICAL / Evidence-Based Medicine; MEDICAL / Internal Medicine; Electronic books; Electronic books
• Languages: English
• ISBNs: 9783030048167; 3030048160
• Related ISBNs: 9783030048150
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from PDF title page (EBSCO, viewed March 22, 2019).; Note: Vendor-supplied metadata.
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.