Hepatitis C virus. Infection and disease / II, (2016)

• Record Type: Book
• Other Titles: Infection and disease
• Further Information: Note: Tatsuo Miyamura, Stanley M. Lemon, Christopher M. Walker, Takaji Wakita, editors.
• Editors: Miyamura, Tatsuo; Lemon, Stanley M; Walker, Christopher M; Wakita, Takaji
• Contents: Contributors; Part I: Chronic Hepatitis C; Natural History of Chronic Hepatitis C; 1 Introduction; 2 Outcome of Acute Hepatitis C; 2.1 Clinical Course; 3 Outcome of Chronic Infection; 3.1 Retrospective Studies; 3.2 Prospective Studies; 3.3 Retrospective-Prospective Studies; 3.3.1 Studies Among Young Women; 3.3.2 Studies Among Young Children; 3.3.3 Studies of Post-Transfusion Hepatitis C; 3.3.4 Studies of Community Acquired HCV Infection; 4 Fibrosis Progression; 5 Natural History of HCV-Related Cirrhosis. 6 Factors that Affect the Rate of Disease Progression and Outcome of Chronic Hepatitis C6.1 Host Factors; 6.1.1 Age at Infection; 6.1.2 Gender; 6.1.3 Race/Ethnicity; 6.1.4 Steatosis; 6.1.5 Non-alcoholic Steatohepatitis; 6.1.6 Insulin Resistance/Diabetes; 6.1.7 Obesity; 6.1.8 Genetics; 6.1.9 Exercise; 6.1.10 ALT; 6.2 Viral Factors; 6.2.1 Co-infection with HBV; 6.2.2 HIV; 6.2.3 HCV Genotype; 6.2.4 Viral Load; 6.3 Environmental Factors; 6.3.1 Alcohol; 6.3.2 Smoking; 6.3.3 Cannabis; 6.3.4 Caffeine; 7 Summary; References; The Multifaceted Features of HCV Infection Beyond the Liver; 1 Introduction. 2 Manifestations Associated with HCV Infection2.1 Cryoglobulinemia; 2.2 Renal Impairments and Glomerulonephritis; 2.3 Porphyria Cutanea Tarda; 2.4 Sjögrenś Syndrome; 2.5 Diabetes and Insulin Resistance; 2.6 Lipid Metabolism Disturbances and Steatosis; 2.7 Lichen Planus; 2.8 Oral Cancer; 2.9 Malignant Lymphoma; 2.10 Autoimmune Thyroid Disease; 2.11 Idiopathic Interstitial Pneumonitis; 2.12 Myocardial Impairments; 2.13 Moorenś Ulcer; 2.14 Cognitive and Mental Disorders; 2.15 All-Cause Mortality in HCV-Seropositives; 3 Conclusion; References; Hepatic Fibrosis in Hepatitis C; 1 Introduction. 2 Pathogenesis of Fibrosis3 Perpetuation of Liver Injury; 4 Intrahepatic Blood Flow and Fibrosis; 5 Effects of HCV Proteins on Fibrosis; 6 MicroRNAs and Fibrosis; 7 Innate Immune Response and Fibrosis; 8 Contribution of Adaptive Immunity; 9 Histologic Fibrosis; 10 Fibrosis Imaging; 11 Serum Markers of Fibrosis; 12 HCV and HIV Co-infection; 13 Contribution of Other Factors to Fibrosis; 14 Post-Transplantation Fibrosis; 15 Fibrosis Resolution; 16 Effects of HCV Treatment; 17 Anti-fibrotic Therapy; References; Hepatocellular Carcinoma and Hepatitis C Virus; 1 Epidemiology of HCV-Related HCC. 2 The Role of HCV in Hepatocarcinogenesis2.1 Direct Role of HCV in HCC Development; 2.2 HCV Variants and HCC; 2.3 Alcohol and HCV-Related HCC; 3 Genetics of HCV-Related HCC; 3.1 Genetic Mutation and Polymorphism for HCC Susceptibility; 3.2 Profiles of Epigenetic Alterations in HCV-Related HCC; 4 Identified Mechanisms of HCV Proteins in Hepatocarcinogenesis; 4.1 HCV and Oxidative Stress; 4.2 HCV and Hepatocyte Cell Growth; 4.3 HCV and Insulin Resistance; 5 Role of Sex Hormones in HCV-Induced HCC Development; 5.1 Estrogen Axis and HCV-Related HCC; 5.2 Androgen Axis and HCV-Related HCC.
• Publisher Details: Japan : Springer
• Publication Date: 2016
• Extent: 1 online resource (ix, 372 pages), illustrations (some color)
• Subjects: 616.3/623; Hepatitis C virus; HEALTH & FITNESS -- Diseases -- General; MEDICAL -- Clinical Medicine; MEDICAL -- Diseases; MEDICAL -- Evidence-Based Medicine; MEDICAL -- Internal Medicine; Hepatitis C virus; Hepatitis C; Hepatitis C, Chronic; Hepacivirus; Medicine & Public Health; Hepatology; Virology; Infectious Diseases; Public Health; Electronic books
• Languages: English
• ISBNs: 9784431561019; 4431561013; 4431560998; 9784431560999
• Related ISBNs: 9784431560999
• Notes: Note: Includes bibliographical references at the end of each chapters and index.; Note: Online resource; title from PDF title page (SpringerLink, viewed November 3, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.