Innovative medicine : basic research and development /: basic research and development. ([2015])

• Record Type: Book
• Further Information: Note: Kazuwa Nakao, Nagahiro Minato, Shinji Uemoto, editors.
• Editors: Nakao, Kazuwa, 1948-; Minato, Nagahiro; Uemoto, Shinji
• Other Names: Uehara Memorial Foundation Symposium
• Contents: Part I: Basic research for innovative medicine. Diverting Glycolysis to Combat Oxidative Stress -- Metabolic Regulation by Nuclear Receptors -- Fighting Fire with Fire in Cancer -- Linear Polyubiquitination: a Crucial Regulator of NF-kB Activation -- VCP, a major ATPase in the cells, as a novel drug target for currently incurable disorders -- Roles of E-cadherin in hepatocarcinogenesis -- The hippo signaling pathway: a candidate new drug target for malignant tumors -- Inhibitory immunoreceptors on mast cells in allergy and inflammation -- Doxycycline-inducible Autoimmune Blistering Skin Disease Model -- T-cell Senescence and Autoimmunity -- Part II: Translational research for innovative medicine. IL-6: A new era for the treatment of autoimmune inflammatory diseases -- Pathogenesis of Non-alcoholic Steatohepatitis and Its Potential Therapeutic Strategies -- Multifaceted translational approach of major mental illness -- Translational research of leptin in lipodystrophy and its related diseases -- Translational research of the activation of the C-type natriuretic peptide (CNP)-guanylyl cyclase-B pathway for skeletal dysplasia -- Clarity and challenges in tissue fibrosis -- TRP channels: their function and potentiality as drug targets -- Autophagic Cell Death and Cancer Chemotherapeutics -- Adrenomedullin as a potential therapeutic agent for refractory ulcerative colitis -- RNA activation -- Part III: New technology for innovative medicine. Cardiac reprogramming for heart repair -- Development of a new in vivo optical probe for biological diagnosis and therapy -- Introduction of mesenchymal stem cells for liver surgery (hepatectomy and transplantation) -- Synaptic and axonal plasticity induction in the human cerebral cortex -- TIM-3 is a novel therapeutic target for eradicating acute myelogenous leukemia stem cells -- TGF-beta LAP degradation products, a novel biomarker and promising therapeutic target for liver fibrogenesis -- Cell-based regenerative therapy for liver disease.
• Publisher Details: Tokyo : SpringerOpen
• Publication Date: 2015
• Copyright Date: 2015
• Extent: 1 online resource (ix, 339 pages), illustrations
• Subjects: 610.28; Medical innovations; Translational Medical Research; Biomedical Research; Biomedical Technology; Medical innovations; Congress; Electronic books
• Languages: English
• ISBNs: 9784431556510; 4431556516
• Related ISBNs: 9784431556503; 4431556508
• Notes: Note: Includes bibliographical references.; Note: Online resource; title from PDF title page (SpringerLink, viewed April 19, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.