Etiology and morphogenesis of congenital heart disease : from gene function and cellular interaction to morphology /: from gene function and cellular interaction to morphology. ([2016])

• Record Type: Book
• Further Information: Note: Toshio Nakanishi, Roger R. Markwald, H. Scott Baldwin, Bradley B. Keller, Deepak Srivastava, Hiroyuki Yamagishi, editors.
• Editors: (Of Tōkyō Joshi Ika Daigaku), Nakanishi, Toshio; Markwald, Roger R; Baldwin, H. Scott; Keller, Bradley B; (Pediatric cardiologist), Srivastava, Deepak; Yamagishi, Hiroyuki
• Contents: Part I. From molecular mechanism to intervention for congenital heart diseases, now and future -- Reprogramming approaches to cardiovascular disease: from developmental biology to regenerative medicine -- The arterial epicardium, a developmental approach to cardiac disease and repair -- Cell sheet tissue engineering for heart failure -- Future treatment of heart failure and pathophysiological analysis of various heart diseases using human iPS cell-derived cardiomyocytes -- Congenital heart disease: in search of remedial etiologies -- Part II. Left-right axis and heterotaxy syndrome -- Left-right asymmetry and human heterotaxy syndrome -- Roles of motile and immotile cilia in left-right symmetry breaking -- Role of cilia and left-right patterning in congenital heart disease -- Pulmonary arterial hypertension in patients with heterotaxy /polysplenia syndrome -- Part III. Cardiomyocyte and myocardial development -- Single cell expression analyses of embryonic cardiac progenitor cells -- Meis1 regulates post-natal cardiomyocyte cell cycle arrest -- Intercellular signalling in cardiac development and disease: NOTCH -- The epicardium in ventricular septation during evolution and development -- S1P-S1p2 signaling in cardiac precursor cells migration -- Myogenic progenitor cell differentiation is dependent on modulation of mitochondrial biogenesis through autophagy -- The role of the thyroid in the developing heart -- Part IV. Valve development and diseases -- Atrioventricular valve abnormalities: From molecular mechanisms underlying morphogenesis to clinical perspective -- Molecular mechanisms of heart valve development and disease -- A novel role for endocardium in perinatal valve development: Lessons learned from tissue specific gene deletion of the Tie1 receptor tyrosine kinase -- The role of the epicardium in the formation of the cardiac valves in the mouse -- TMEM100, a novel intracellular transmembrane protein essential for vascular development and cardiac morphogenesis -- Cell autonomous regulation of BMP-2 in endocardial cushion cells during AV valvuloseptal morphogenesis -- Part V. The second heart field and outflow tract -- Properties of cardiac progenitor cells in the second heart field -- Nodal signaling and congenital heart defects -- Utilizing zebrafish to understand second heart field development -- A history and interaction of outflow progenitor cells implicated in "Takao syndrome" -- The loss of Foxc2 expression in the outflow tract links the interrupted arch in the conditional Foxc2 knockout mouse -- Environmental modification for phenotype of truncus arteriosus in Tbx1 hypomorphic mice -- Part VI. Vascular development and diseases -- Extracellular matrix remodeling in vascular development and disease -- The "cardiac neural crest" concept revisited -- Roles of endothelial Hrt genes for vascular development -- Placental expression of type 1 and 3 inositol trisphosphate receptors is required for the extra-embryonic vascular development -- Tissue remodeling in vascular wall in Kawasaki disease-related vasculitis model mice -- Part VII. Ductus arteriosus -- Progerin expression during normal closure of the human ductus arteriosus: A case of premature ageing? -- The multiple roles of prostaglandin E2 in the regulation of the ductus arteriosus -- Developmental differences in the maturation of sarcoplasmic reticulum and contractile proteins in large blood vessels influences their contractility -- Fetal and neonatal ductus arteriosus is regulated with ATP-sensitive potassium channel -- Part VIII. Conduction system and arrhythmia -- Regulation of vertebrate conduction system development -- Cardiac Pacemaker Development from a Tertiary Heart Field -- Endothelin receptor type A expressing cell population in the inflow tract contributes to chamber formation -- Specific isolation of HCN4 positive cardiac pace-making cells derived from embryonic stem cell -- Part IX. Current molecular mechanism in cardiovascular development -- Combinatorial functions of transcription factors and epigenetic factors in heart development and disease -- Pcgf5 contributes to PRC1 (Polycomb repressive complex 1) in developing cardiac cells -- Non-coding RNAs in cardiovascular disease -- Part X. iPS cells and regeneration in congenital heart diseases -- Human pluripotent stem cells to model congenital heart disease -- Engineered cardiac tissues generated from immature cardiac and stem-cell derived cells: Multiple approaches and outcomes -- Dissecting the left heart hypoplasia by pluripotent stem cells -- Lentiviral gene transfer to iPS cells; toward the cardiomyocyte differentiation of Pompe disease-specific iPS cells -- Molecular analysis of long-term cultured cardiac stem cells for cardiac regeneration -- Epicardial contribution in neonatal heart regeneration -- Part XI. Current genetics in congenital heart diseases -- Genetic discovery for congenital heart defects -- Evidence that deletion of ETS-1, a gene in the Jacobsen syndrome (11q- ) cardiac critical region, causes congenital heart defects through impaired cardiac neural crest cell function -- Notch signaling in aortic valve development and disease -- To detect and explore mechanism of CITED2 mutation and methylation in children with congenital heart disease.
• Publisher Details: [Tokyo] Japan : Springer Open
• Publication Date: 2016
• Copyright Date: 2016
• Extent: 1 online resource (xii, 383 pages), illustrations (some color)
• Subjects: 616.1/2043; Congenital heart disease -- Etiology; Cardiology; Children -- Surgery; Embryology; Medicine; Pediatrics; Medical profession; Heart Defects, Congenital -- etiology; Electronic books; Congress
• Languages: English
• ISBNs: 9784431546283; 4431546286
• Related ISBNs: 9784431546276; 4431546278
• Notes: Note: Includes bibliographical references and index.; Note: Online resource; title from pdf title page (SpringerLink, viewed December 6, 2016).
• Access Rights: Legal Deposit; Only available on premises controlled by the deposit library and to one user at any one time; The Legal Deposit Libraries (Non-Print Works) Regulations (UK).
• Access Usage: Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force.